Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Phosphatidylinositols"”.
-
Investigation of Phosphatidylinositols and Phosphoinositides Using Matrix- Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
… in health and disease. This thesis focuses on phosphatidylinositols (PIs) and their phosphorylated forms, phosphoinositides (PIPs), which are critical regulators of cellular signaling, membrane dynamics, and cytoskeletal organization. Dysregulation of PIs and PIPs are implicated in various …
-
MYO1C Binds to PiP2 With High Affinity Through a Putative Ph Domain
… PH domain that binds tightly and specifically to phosphatidylinositols.
-
Novel Insights into the Role of the Smoothened Cysteine Rich Domain in Hedgehog Signalling
… that the fatty-acid side chains of the phosphatidylinositols interact with Smo CRD, and PI(4)P specifically enhances activator induced Hh signalling. Therefore, we speculated that PI(4)P may function to bridge the Smo extracellular and the membrane spanning domains, wherein the …
-
Illuminating Organellar and Molecular Organization of the Endomembrane System
The endomembrane system consists of virtually all of the structurally and functionally distinct membrane compartments in a eukaryotic cell, except mitochondria and plastids. Different compartments in the endomembrane system communicate with each other through vesicular transport as well as direct …
-
Applications of metabolomics to study the pathophysiology of adverse pregnancy outcomes
… 1 lyso phosphatidylglycerophosphate, 2 phosphatidylinositols, 2 phosphatidylglycerophosphates, and 3 phosphatidylglycerols) in at 20 weeks of gestation were associated with the development of SGA in the Cork participants of the SCOPE pregnancy cohort. Chapter 4 demonstrated that …