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Showing 1 to 2 of 2 for “"Phosphatidylinositol 4-kinase III beta"”.
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The Function of Phosphatidylinositol 4-Kinase III-Beta in Trypanosoma Brucei
Phosphatidylinositol 4-kinase phosphorylates phosphatidylinositol at the D4 position resulting in phosphatidylinositol 4-monophosphate. Subsequent phosphorylation events result in a group of molecules known as phosphoinositides. These molecules are important in signal transduction, endocytosis, …
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A Role for the Phosphoinositide Lipid Kinase PI4KIIIbeta in Breast Oncogenesis and Akt Activation
The lipid kinase phosphatidylinositol 4-kinase III β (PI4KIIIβ) phosphorylates phosphatidylinositol (PtdIns) to generate PI(4)P in the Golgi. PI4KIIIβ is likely involved in the development of breast cancer as it has been reported genetically amplified in a subset of human breast tumours and is a …