NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 6 of 6 for “"Phosphatase PTEN"”.

  1. Pten Signaling in Regulatory T Cells and Inflammatory Disease

    Shrestha, Sharad Krishna2018

    … In this study, we determined the role of the phosphatase PTEN in Treg cells. We found that specific depletion of PTEN in Treg cells results in excessive TH1 and T follicular helper cells (TFH) responses, associated with elevated germinal center (GC) B cells and spontaneous development of …

    tenn-hsc Repository record

  2. Stress-induced remodeling of the caenorhabditis elegans dauer

    Androwski, Rebecca JoannUniversity of Illinois at Urbana-Champaign2021

    … including the FOXO transcription factor/DAF-16, phosphatase PTEN/DAF-18 and Cytochrome P450/DAF-9. Finally, we find that the TOR associated protein, RAPTOR/DAF-15 regulates mutually exclusive branching of the IL2 and FLP dendrites. Together, our results shed light on molecular processes that …

    uiuc Repository record

  3. A dissection of class I phosphoinositide 3-kinase signalling in mouse embryonic fibroblasts and prostate organoids

    Sadiq, Barzan A.University of Cambridge2018

    … by the tumour-suppressor and PI(3,4,5)P3-3-phosphatase PTEN, or modified to a distinct PI(3,4)P2 signal, by SHIP-family 5-phosphatases. The PI(3,4)P2 is removed by INPP4-family 4-phosphatases. Published work has shown that PI(3,4,5)P3 signalling can also occur in endosomes and nuclei, …

    cambridge Repository record

  4. DISSECTING THE FUNCTION AND INTERACTOME OF PLEKHS1 IN PROSTATE TUMORIGENESIS

    Jung, Piotr KrzysztofUniversity of Cambridge2021

    … levels. Loss of the tumour-suppressor and PIP3-3-phosphatase PTEN, leads to constitutive activation of the PIP3-network and is a very common event in many human tumours, including prostate cancer. Mouse models in which Pten and/or Class I PI3K signalling can be conditionally deleted in the …

    cambridge Repository record

  5. Kollagen Typ I induziert die Phosphorylierung von Cateninen und die Dissoziation des E-Cadherin-Catenin-Komplexes in Pankreaskarzinomzelllinien.

    Müller, ClaudiaUniversität Ulm

    ulm-diss Repository record

  6. Caractérisation du STF-62247 comme un inhibiteur de PIKfyve dans les carcinomes rénaux à cellules claires

    Maillet, ThomasUniversité de Moncton2024

    … a été prévenu par un traitement à la lambda phosphatase, suggérant ainsi que le STF-62247 engendre une phosphorylation de PIKfyve par un mécanisme qui nécessite encore plus d'investigation. Cette modification n'a pas été observée dans les types de cancer insensibles au STF-62247 avec le gène …

    moncton Repository record