Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Pheophorbide a"”.
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"The Regulation of Pheophorbide a Oxygenase (Pao) in the ""Green Seed"" Problem in Canola and During Leaf Senescence"
… by freezing conditions have been identified. Pheophorbide a oxygenase (PaO) is considered to be a key enzyme in regulating chlorophyll degradation. Pheophorbide a, the substrate of PaO, and other chlorophyll catabolites from canola seeds accumulated after exposure to freezing conditions. …
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Evidence for reversible phosphorylation as a post-translational regulatory mechanism in the chlorophyll catabolic pathway
… governing activity of one enzyme in particular, pheophorbide a oxygenase (PaO), is especially desirable as PaO catalyzes the oxidative opening of the porphyrin ring structure, considered to be the key regulatory point in chlorophyll degradation. Through site-directed mutagenesis of the …
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Study of porphyrins and heterodimers targeting ABCG2 transporter and development of a multiplexed flow cytometric approach for detection of anti SARS-CoV-2 IgG, IgM and IgA
… distinto entre porfirina 4B e o substrato Pheophorbide a. Pheophorbide a foi capaz de ligar-se em três regiões diferentes da proteína enquanto 4B apresentou apenas região de interação na proteína, apresentando forte interação iônica com aminoácido GLU446. A inibição foi seletiva já que não …
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To Investigate The Impact Of Gut Bacteria On Efflux Transporter Expression And Function In Gastrointestinal Mucosae
… showed a higher uptake of the BCRP probe Pheophorbide-A (Phe A) within the enterocytes as compared to humanized mice colonoids. These results correlated with Immunohistochemistry experiments that showed a lower expression of BCRP in germ free colon compared to humanized mice colon. These …
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Understanding the Impact of BCRP and PGP Efflux Transporters on the Disposition of Their Endogenous, Xenobiotic and Dietary Substrates
… Finally, utilizing a Bcrp dietary substrate, Pheophorbide A (PhA), we developed an <em>in vivo </em>assay for the assessment of DDI due to inhibition of Bcrp at enterocytes. Our results demonstrated that PhA can be potentially used to create a reliable, high-throughput and less expensive …
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Computational analysis of upstream regulatory elements regulating plant chlorophyll degradation
… degradation pathway involves the enzyme pheophorbide a oxygenase (PAO), which oxidizes the chlorophyll degradation intermediate pheide a, that is eventually converted to non-fluorescent chlorophyll catabolites (NCCs). PAO activation in maturing green seeds is known to be disrupted …