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Showing 1 to 5 of 5 for “"Phenylhydrazone"”.

  1. Investigating the role of the Nrf2-Keap1 pathway in mitophagy

    … with carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), an uncoupler of oxidative phosphorylation. PINK1 did not influence Nrf2 transcript, protein levels, half-life, subcellular localisation or transcriptional activity. However, FCCP induced Nrf2 at the transcript and protein …

    dundee Repository record for Investigating the role of the Nrf2-Keap1 pathway in mitophagy (opens in a new tab)

  2. Chemical probes for the study of mitochondrial oxidative stress

    … FCCP (carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone) in its ionised form. New analogues of FCCP-SUM viii are now in development to enable targeting to mitochondria.

    glasgow Repository record for Chemical probes for the study of mitochondrial oxidative stress (opens in a new tab)

  3. Photoredox activation of SF₆ for fluorination, on-demand automated titration of organometallic reagents in continuous flow, and progress toward an enantioselective synthesis of bedaquiline

    … 4-phenylbenzylidene benzylamine, salicylaldehyde phenylhydrazone) can be used for the titration of a wide array of organometallic species (RLi, RMgX, MHMDS) in molarities ranging from 0. 1M to 4.9M. In removing user intervention from the titration process, the developed system greatly reduces the …

    mit Repository record for Photoredox activation of SF₆ for fluorination, on-demand automated titration of organometallic reagents in continuous flow, and progress toward an enantioselective synthesis of bedaquiline (opens in a new tab)