Global ETD Search
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Showing 1 to 2 of 2 for “"Phenotype heterogeneity"”.
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Novel Machine Learning Models for Identification, Characterization and Prioritization of Phenotype-Genotype Associations
… and prioritizing molecular and functional phenotype effects of genetic variants. I first investigate the problems caused by phenotype heterogeneity in association studies of complex traits. Many complex diseases, such as autism, diabetes and cancer, are very heterogeneous in terms of the …
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Estimating genetic and environmental sources of variance for depression
… These findings highlight the substantial heterogeneity of MDD, which may further impede the search for genetic causes. There is therefore an urgent need to increase sample sizes and to refine and stratify the phenotype to reduce heterogeneity of phenotypic measurements, and measurement …