Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Phase-specific"”.
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Control of M-G1 phase-specific expression in fission yeast
… co-ordinate progression through its individual phases, safeguarding the timing and integrity of its hallmark events, DNA synthesis and mitosis. Transcription is prominent among these processes, manifesting its importance for cell cycle controls by the large number of eukaryotic genes that are …
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Identification and isolation of growth-phase specific proteins of mycobacteria
The aim of this project was to identify growth phase-specific heat shock proteins of Mycobacterium smegmatis LR222. A growth curve was constructed using the ATP assay. This method was shown by B. A. Ntolosi to be the most accurate indicator of when the organism entered the various phases of growth. …
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Antigenic Variation in Candida Albicans
The antigenicity of the germ tube and the yeast phase of Candida albicans have been compared by crossed immunoelectrophoresis, tandem-crossed immunoelectrophoresis and classical immunoelectrophoresis. Qualitative and quantitative differences between the two growth forms have been observed. One …
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PAH and PCB distribution in sediment fractions and sorptive phases
… contaminant loading of each of the sorptive phases. Bioavailability of contaminants in oil and grease, soot and organic carbon, components of sediment total organic carbon (TOC), may be vastly different. Physical properties are also different and determine fate during treatment. This study …
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The splicing inhibitor Isoginkgetin leads to defects in multiple phases of the cell cycle
… p53 expressing cells exhibited a remarkable S phase defect while the p53-null subline accumulated with 4C DNA content. Despite the pronounced difference in these isogenic strains, there was no pronounced p53 transcriptional response as assessed by qRT-PCR and preliminary microarray analysis. …
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Multi-Proxy Records of Climate and Carbon Cycle Perturbations in the Paleozoic: Integrating Isotope Geochemistry and Sedimentology
… the extent to which diagenesis and facies- and phase-specific effects drive a major Early Mississippian carbon isotope excursion. In aggregate, this thesis outlines a roadmap for assessing changes to climate and the carbon cycle for carbonate rocks in the Paleozoic.
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Mechanisms of Cell Death Initiated in Herpes Simplex Virus Thymidine Kinase Expressing Colon Tumor Cells Treated with Ganciclovir and UCN-01
… Colon tumor cells treated with GCV arrest in S-phase, and cells treated with the combination of UCN-01 and GCV also undergo S-phase specific cell death. However, UCN-01 treatments induced the disappearance of key mitotic proteins and had variable effects on the cell cycle.</p>
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Healthy by Design: Development of a Biophilia Design Decision Support Framework
… Framework evolutions help identify design-phase-specific knowledge gaps. This study finds that a deficiency in early exposure to a priori, explicit and tacit biophilic knowledge is creating a critical gap, thus diminishing a posteriori biophilic knowledge and research in the architecture …
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Multi-modal characterization of cements and irradiated granites
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Understanding variability in performance of type il cements: insights from Raman imaging
… because commercial PLCs differ in both clinker phase composition and fineness. This thesis investigates twelve commercial Type IL cements to quantify their performance variability and understand how their physical and chemical properties influence it. Multimodal characterization was applied, …
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Microscopic Strain Localization and Damage in Multi-phase Alloys
… strain localization and damage in multiphase alloys is challenging. In addition to distinct phase-specific properties, extra complexities arise from a broad spectrum of morphology and spatial distribution of phases. Multiple deformation mechanisms can also occur simultaneously, which …
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Wildfire Risk Management for Informal Settlements in Chile
… on these findings, the research culminates in phase-specific actionable policy recommendations addressing the compound vulnerabilities of informal communities through: 1) enhanced shelter capacity estimation methodologies; 2) formalized private sector involvement; 3) integrated tsunami-wildfire …
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A Patient-Oriented Exploration of Women's Perspectives on Surgeon Continuity in Breast Cancer Care
… communication, information, and preparedness; phase-specific preferences for continuity and team-based care; navigating fragmented systems and the burden of self-advocacy; post-surgical support and standard of care; and diagnosis communication through eHealth. Women described continuity with …
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A mixed method Delphi study to determine professional consensus on the key elements of outpatient Psychodynamic Group Psychotherapy (PGP) for psychosis
… approach throughout assessment and therapy, phase specific interventions and attitudes and qualities necessary for therapists conducting PGP for psychosis. 145 components were endorsed as important or essential for PGP for psychosis by more than 80% of the experts. The participants' comments …
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An improved directed random walk framework for cancer classification using gene expression data
… can be further divided into data pre-processing phase, specific tuning parameter selection, weight as additional variable, and exclusion of unwanted adjacency matrix. Besides that, SDW also incorporated four directed graphs to study the usability of the directed graph. The best directed graph …
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The Origin of Genome Instability in Cancer: Role of the Fragile Site Gene Product FHIT
… thymidine triphosphate. FHIT up-regulates the S-phase-specific expression of thymidine kinase 1, a component of the pyrimidine salvage pathway for the production of thymidine triphosphate. Balanced precursors of DNA are needed for efficient and accurate DNA replication, and notably restoration of …
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Compartmental Hepatitis B Virus (HBV) Evolution, Replication and Infectivity in vivo and ex vivo
… that HBV evolved in a compartment- and disease phase-specific fashion. However, the effect of nucleos/tide analogue (NA) therapy on HBV evolution and replication in different compartments (i.e., liver, plasma and peripheral blood mononuclear cell (PBMC)) is unknown, as well as the replicative …
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Increasing IFN-[gamma] productivity in CHO cells through CDK inhibition
… arrest. In this study, we have shown that the specific inhibition of the CDK2-CcnE complex through chemical inhibition leads to growth arrest and a subsequent increase in specific productivity. In addition, we have shown that the knockdown of CcnEl alone leads to increases in specific …
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Modeling the Sit-to-Stand Transition using Koopman Lifting Linearization and Human State Estimation
… of STS. To coherently capture the multi-phase nature of STS, lifting linearization, a dynamic modeling methodology inspired by Koopman operator theory, to subsume segmented local dynamics in a globally linear dynamic model. A novel class of lifting linearization basis functions, termed …
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Action Intention Modulates the Temporal Dynamics of Object Feature Representation: An Electrophysiological Approach
… viewed real 3D objects in an action planning phase and either grasped or touched the objects with their knuckle (“knuckling). I then applied time-resolved multivariate analyses to the EEG data to infer the time course of the representation of objects’ visual features. I found that although …
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