Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Phase response curve"”.
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Mathematical Modeling of Circadian Rhythms in Drosophila melanogaster
… of ambient temperature. Finally, they are phase shifted by light. The circadian rhythm can be either advanced or delayed by applying a pulse of light in constant darkness. Consequently, the circadian rhythm will synchronize to a periodic light-dark cycle, provided the period of the driving …
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Analysis of Circadian Rhythm Using a Novel SCN-Specific Cre Transgenic Mouse Line
… individually oscillate with various period, phase, and amplitude. These conflicting results can be reconciled if inter-neuronal networking in the SCN is required for a consolidated behavioral circadian rhythm. To test this hypothesis, a novel SCN-specific Cre transgenic mouse line, named …
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Analysis and reduction of a modeled bursting neuron
… of the saddle-node bifurcation. The response to the model to perturbatory current pulses was analyzed in the state-space of the slow variables. To aid in the analysis nullclines were calculated, including "average" nullclines, which are the nullclines of the slow-variables averaged …
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Dynamical systems and their applications in neuroscience
… suggest an improved version. We introduce the Phase Response Curve (PRC), which is a curve that describes the effect of an input on a periodic orbit. We derive an efficient method to compute this PRC. The extended functionalities of MatCont, a software package for the study of dynamical systems …
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A study of phase resetting, mutual entrainment, and modified ventricular parasystole using a model of coupled heart cells
… aspects of cardiac electrophysiology including phase-resetting and entrainment are investigated through the dynamic interactions of coupled mathematical models of cardiac cells. Unlike previous studies of cell interaction which have used simplified models of a general cardiac cell or oscillators …
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Dynamics of phase locking in neuronal networks in the presence of synaptic plasticity
… generated by neuronal networks depends on the phase relationships of its individual neurons. Observed phases result from the combined effects of individual cells and synaptic connections whose properties change dynamically. The properties of individual cells and synapses can often be …
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The roles of vasoactive intestinal polypeptide in circadian entrainment of suprachiasmatic nucleus
… at different circadian time points to generate a phase response curve which reliably predicted the phase relationship between the SCN and daily increases in VIP. VIP shifted PER2::LUC rhythms in time- and dose-dependent manner. VIP rapidly increased intracellular cAMP in most SCN neurons and …
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The Effect of General Anaesthesia on Circadian Rhythms in Mice
… To do so, I collected data to construct a full phase response curve (PRC) for each anaesthetic agent. Animals received either a six-hour GA treatment or a 10-minutes GA treatment (control group) with isoflurane (1.5%) or sevoflurane (2.6%). 80 mice were treated with isoflurane for six hours and …