Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 131 for “"Pharmacotherapy"”.
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Modern Pharmacotherapy of Rheumatoid Arthritis
Rheumatoid Arthritis is one of the leading causes of disability in the world. This thesis describes the diagnostic procedure for this disease as well as the standard treatment protocol. Almost half of the patients treated with the golden standard fail to meet treatment goals and thus require a more …
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A systematic approach to improving pharmacotherapy in the elderly
… structured and systematic approach on improving pharmacotherapy in the elderly (the LIMM-model) would lead to a more appropriate and accurate drug use in the elderly. The elderly use many drugs and are more prone to suffer from adverse drug reaction. It is therefore important to address the …
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Quantitative assessment of the pharmacotherapy of biopolar disorder and schizophrenia
… into interindividual variability in response to pharmacotherapy, In clinical trials of acute mania, a number of measures have been used to assess the severity of illness and its response to treatment. Rating instruments need to be validated in order for a clinical study to provide reliable and …
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Psychotherapy and Pharmacotherapy for Social Anxiety Disorder: A Comprehensive Meta-Analysis
… of cognitive behavioral therapy (CBT) and/or pharmacotherapy for social anxiety disorder. Though there have been numerous trials in the past decade, no meta-analysis examining both psychotherapy and pharmacotherapy for social anxiety disorder has been published since 2001. For the present …
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Efficacy of Cognitive Therapy and Pharmacotherapy In Depression: A Meta-Analysis
… of cognitive behavioral therapy (CBT) and pharmacotherapy in preventing relapse following treatment discontinuation was performed using published studies of depressed participants. Twenty-three articles met inclusionary criteria and were included in the analyses. Weighted effect sizes and …
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Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy.
Biomarkers have potential utility in the treatment of pain as diagnostics and for quantification of drug efficacy and safety. A qualified biomarker will capture overlapping disease mechanisms and will be responsive to treatment. The necessity for these strict requirements renders it difficult to …
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Applying quantitative methods in the assessment of outcomes of pharmacotherapy of psoriasis
Healthcare providers and policy makers are faced with an ever-increasing number of medical publications. Searching for relevant information and keeping up to date with new research findings remains a constant challenge. It has been widely acknowledged that narrative reviews of the literature are …
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Pharmacotherapy in frail older patients in acute care settings: medicines utilisation and optimisation
Background: Frailty is the most problematic syndrome among older people. It is multifactorial and characterised by decreased reserve and resistance against internal and/or external stressors. Frail patients are at increased risk of adverse drug events, polypharmacy, potentially inappropriate …
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Drug-related problems in the elderly - Interventions to improve the quality of pharmacotherapy
Introduction: Elderly people, in particular those residing in nursing homes, often use many drugs. In general elderly patients are at greater risk of experiencing drug-related problems (DRP), as they have multiple diseases, are using many drugs and have changed physiological status. Objectives: To …
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Transcendental meditation on blood pressure in hypertensive patients as an alternative/adjuvant to pharmacotherapy
The most important modifiable risk factor in reducing all-cause morbidity and mortality is systemic arterial hypertension. Elevated blood pressures are associated with greater risks of cardiac disease. Less than half of the population with hypertension are aware of their diagnosis and those who are …
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Healthcare Resource Utilization and Costs Associated with Non-Adherence to Pharmacotherapy for Major Depressive Disorder
… antidepressants; however, non-adherence to MDD pharmacotherapy is common and is associated with poorer clinical outcomes. OBJECTIVE: To assess the impact of non-adherence to MDD pharmacotherapy on healthcare resource use (HCRU) and costs in MDD patients enrolled in commercial, Medicare …
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Pharmacotherapy in older people receiving palliative care in hospice settings: prescribing, deprescribing and medicines optimisation
Multimorbidity is common in older patients. Consequently, polypharmacy and potentially inappropriate prescribing (PIP) are prevalent and increase toward the end of life (EOL). One potential solution is deprescribing, a supervised discontinuation of inappropriate medicines. The overall aim of this …
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Knowledge, attitutes and practices of medical doctors on pharmacotherapy for smoking cessation in Khomas region, Namibia
… (LMIC). Inspite that smoking cessation (SC) pharmacotherapy significantly reduces poor outcome, access to smoking cessation services in medical practice in Namibia is unknown. The study aims to assess the knowledge, attitudes and practice of SC pharmacotherapy among medical doctors in Khomas …
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Biomechanical Analysis of Human Coronary Atherosclerotic Plaques in Response to Pharmacotherapy, and in Predicting Adverse Clinical Events
… thesis first demonstrates that PSS changes with pharmacotherapy, in particular, high-intensity statin (HIS) treatment prevented the rise in PSS in most advanced lesions (those with plaque burden [PB]>60%). The change in PSS was both dependent on drug therapy and baseline disease severity, and the …
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Pharmacotherapy for Social Anxiety Disorder and Posttraumatic Stress Disorder: New Meta-Analytic Approaches to Synthesising the Evidence
… objectives 1) To update Cochrane reviews of pharmacotherapy for SAD and PTSD, 2) To conduct a qualitative systematic review of network meta-analyses for pharmacological treatment of common mental disorders, 3) To conduct network meta-analyses for SAD and for PTSD and to compare findings to …
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Design, synthesis, and biological evaluation of sigma receptors (σRS) ligands as potential pharmacotherapy for cancer and drug addiction
Sigma receptors are a well-defined unique class of receptors and are highly expressed in the central nervous system and also widely distributed in peripheral organs and tissues. There are two subtypes of sigma receptors: sigma-1 and sigma-2. These receptors are thought to be associated with …
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