Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 89 for “"Pharmacological interventions"”.
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Pharmacological Interventions in Atrial Fibrillation
Atrial fibrillation arises when abnormal electrical signals suddenly initiate within the atria, taking precedence over the heart's natural pacemaker, which can no longer regulate the heart's rhyth. This leads to irregular and often excessively fast contractions of the atrial heart muscle cells, …
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Pharmacological interventions against myocardial ischemia and reperfusion injury
… Aims: To investigate whether two different pharmacological interventions, cyclosporine A (CsA) and the novel enkephalin analogue EP 94, could reduce myocardial infarct size in different porcine models of myocardial ischaemia and reperfusion. Furthermore, to examine the distribution of the …
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EXERCISE AND NON-PHARMACOLOGICAL INTERVENTIONS TO IMPROVE METABOLIC HEALTH AND WELL-BEING IN CHRONIC CONDITIONS
Physical activity is known to improve metabolic profile and mental well-being in the general population and in individuals affected by various chronic conditions. Type, timing, intensity and frequency of exercise are important to warrant adherence and to optimize results in subjects affected by …
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Regulation of Substrate Metabolism and Renin-Angiotensin System with Dietary and Pharmacological Interventions: Implications for Obesity and Related Disorders
… this parameter. In our final study, we used a pharmacological intervention (the adiponectin mimetic ALY688) to alter AT glucose and fat metabolism. Despite not altering glucose uptake in Epid or Sc Ing adipocytes, ALY688 significantly enhanced glucose oxidation. Together, these projects explore …
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Comparative effectiveness of non-pharmacological interventions for preventing cognitive decline in older adults: a systematic review and network meta-analysis
… controlled trials evaluating lifestyle interventions in older adults at risk of dementia. Searches of PubMed, PubMed Central, Clinicaltrials.gov, and Cochrane Library (collection to February 2026) identified 18 trials (n = 10,405). Interventions included aerobic exercise, …
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The Nurses' Experience Using Non-pharmacological Interventions for Persons Living with Dementia in Rural Long-Term Care Facilities in Saskatchewan
… diagnoses of dementia. Evidence recommends nonpharmacological interventions (NPIs) as the first line of defense to treat RB, yet indicates it is not always being used. Nurses working in LTCF have direct impact on decisions of care, including interventions for RB. Minimal research exists …
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A mixed methods exploration into the management of behavioural and psychological symptoms of dementia in care homes: care approaches, strategies and psychotropic medications
… in their use for people with dementia. Non-pharmacological interventions have been recommended as safer alternatives. The aim of this study was to explore the strategies used in care homes to manage behavioural and psychological symptoms of dementia. The study used a mixed methods, …
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The Influence of Context on Utilizing Research Evidence for Pain Management in Jordanian Pediatric Intensive Care Units
… of the literature to identify pain management interventions in the PICU; 2. A cross-sectional and multisite survey to determine the current pain management practices, and the availability and content of practice guidelines in Jordanian PICUs; 3. A correlational and multisite survey to examine …
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Cocaine self-administration in rhesus monkeys: effects on neurobiology and cognition and evaluation of cognitive enhancement for addiction treatment
… exist, although combined behavioral and pharmacological interventions, reviewed in Chapter I, may lead to better treatment outcomes. The goal of the current research is to characterize neurobiological and cognitive deficits associated with cocaine use in monkeys, and examine cognitive …
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Towards a Better Understanding of Zebrafish Sleep Behavior
… they were exposed to varying environmental and pharmacological interventions. Animals were exposed to one of three conditions: (1) sustained darkness, (2) sustained brightness, and (3) sustained bright conditions, paired with the administration of an adenosine antagonist. The presentation of …
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A Novel Psychotropic Risk Assessment To Enhance Medical Management Of Patients With Behavioral And Psychological Symptoms Of Dementia
… (CMS, 2013). Expert consensus calls for non-pharmacological strategies as the first line treatment, yet some patients with BPSD may require a combination of non-pharmacological interventions and pharmacological treatments for symptom reduction (AGS, 2011). The relief of debilitating symptoms …
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Effects of dry needling and therapeutic exercise on sleep in individuals with chronic neck pain and sleep disturbance: A pilot randomized clinical trial
… relationship between sleep and pain, non-pharmacological interventions are lacking to address both sleep dysfunction and pain together. Therefore, research that investigates the effects of non-pharmacological interventions not only on pain but also on sleep dysfunction is warranted. As dry …
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Standardizing the screening, assessment, and treatment of mild cognitive impairment in acute care: a multidisciplinary approach
… et al., 2019). Currently, there are no effective pharmacological interventions that offer a long-term effect on delaying the progression from MCI to dementia. There is, however, a growing body of evidence supporting the important role of non-pharmacological interventions in MCI (Hong, et al., …
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Management of treatment resistant depression /
… their efficacy, and highlighting limitations. Pharmacological strategies, including augmentation, combination therapy and antidepressant switching, alongside emerging treatments such as ketamine, psilocybin, buprenorphine, and dextromethorphan and non-pharmacological interventions, encompassing …
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Insomnia symptoms in elderly persons - assessment, associated factors and non-pharmacological nursing interventions
… terms of associated factors and evidence of non-pharmacological interventions in healthcare settings. Data were collected by means of a systematic literature search (Study I), questionnaires (Studies II-III), interviews and observations (Study IV). The results from Study I are based on nine …
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The Best Practice Guideline For theTreatment of Pediatric Diaper Dermatitis
… most effective treatments for diaper dermatitis, pharmacological and non-pharmacological interventions. Thus, health care providers are an essential reference for caregivers and should have appropriate treatment and preventive suggestions for their patients' caregivers. </p><p>The purposes of this …
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The development of a non-pharmacological intervention for delirium management in critically ill patients
… mortality and morbidity. Multicomponent non-pharmacological interventions are beneficial in the prevention and treatment of delirium in older hospitalised patients however, there is a lack of evidence for their efficacy in critically ill patients. The studies in this thesis investigate which …
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A Program Evaluation of the Seniors Who Paint Program
… art programs may serve as more practical interventions to improve the quality of life and cognition in older adults than more traditional or pharmacological interventions. Despite promising results, most studies investigating the impact of participatory arts on older adults have yet to be …
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The role of physical activity and unhealthy diet on ADHD symptoms and emotional well-being in adolescents diagnosed with ADHD
… amount of researches have examined these non-pharmacological interventions on ADHD symptoms and emotional well-being among adolescents diagnosed with ADHD. The aim of this study was to examine this relationship among 13-16 years old adolescents diagnosed with ADHD. The data used in this study …
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Environmental enrichment and serotonergic alterations on depressive-like states in rats
… suffering from depression primarily rely on pharmacological interventions to alleviate the incapacitating symptoms of the disorder. In addition to genetic differences underlying the etiology of depression, environmental factors play a key role as well. For example, environmental enrichment …
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