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Showing 1 to 1 of 1 for “"Pharmacological chaperones"”.

  1. Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter

    … folding and maturation of the transporter. Pharmacological chaperones have previously been used to rescue mutations in other membrane proteins, and we therefore examined the possibility of using pharmacological chaperones to rescue DTDS mutations. We developed a DAT surface expression assay …

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