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Showing 1 to 1 of 1 for “"Pharmacokinetics -- Statistical methods."”.
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Sample size determination for Emax model, equivalence / non-inferiority test and drug combination in fixed dose trials.
Sample size determination is one of the most important aspects in clinical designs. Careful selection of appropriate sample sizes can not only save economic and human resources, but also improve model performance and efficiency. We first explore the sample sizes of Emax model for a simple one group …