Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 193 for “"Pharmaceutics"”.
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Primary and secondary crystal nucleation of pharmaceutics
Control of the crystallisation process is essential in the consistent and reliable production of many particulate materials in the pharmaceutical and chemical industries. Crystal Nucleation defines the crystal size distribution of the obtained crystal population affecting downstream operations. The …
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Computational pharmaceutics approaches to inform drug developability: focus on lipid-based formulations
… of bio-enabling formulations. Computational pharmaceutics is a growing area of research interest to support structured guidance in formulation strategy. Using data-driven modelling, a streamlined roadmap of computational possibilities for development scientists is possible. Accordingly, the …
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Crystal engineering, Bio Pharmaceutics and Cell biology of active pharmaceutical ingredient (drug) nanoparticles. Formation and cell interaction of hydrocortisone and prednisolone nanoparticles.
Nanotechnology applications have emerged enormously in recent times. Of particular interest is that area that overlaps the areas of nanotechnology, biology and medicine: nanomedicine. One advantage of nanomedicines is it that it can be used as an enabling technology by pharmaceutical researchers …
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Signal enhancement and data mining for biological and chemical samples using mass spectrometry
… actively involved in the areas of healthcare, pharmaceutics, environmental analysis, food industry and forensics due to its ability to provide molecular information at trace levels. Recently, because of the complexity of chemical and biological samples, computer-assisted mass spectra analysis, …
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Mechanics of Microparticles in the Context of Structure and Functionality
… for instance, in the fields of medicine and pharmaceutics, but also in terms of the broad domain of composite materials. In this work, force spectroscopy experiments were performed in combination with optical, atomic force and electron microscopy for morphological investigation. Thus, an …
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Characterization, Imaging and Quantitation of Small Molecules by Ambient Ionization Mass Spectrometry
… in the field of forensics, microbiology and pharmaceutics is described. With the optimization of the front end modes, better sensitivity, selectively and robustness was ensured.
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Structural studies of organic crystals of pharmaceutical relevance. Correlation of crystal structure analysis with recognised non-bonded structural motifs in the organic solid state
… pharmaceutical solids that govern the physical pharmaceutics performance of such materials and through the use of structural techniques and correlation of these results with crystal structural database to establish the presence of physical motifs in selected systems. Structural motifs were …
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Computational Discovery of Microstructured Composites with Optimized Trade-Off between Strength and Toughness
… of applications in material science, chemistry, pharmaceutics, robotics, etc.
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Self-sorting of deformable particles in a microfluidic circuit
… for research and industrial applications (e.g., pharmaceutics, food industry, etc.). The device design is carried out using an equivalent resistance model, and numerical simulations are used to validate the design. The device is fabricated in PDMS, flow velocities are characterized using particle …
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Optimization of Optical Nanosensor Response for the Detection of Anthracyclines Using a Binary Machine Learning Classifier
… that monitor the pharmacokinetics of active pharmaceutics to decrease toxicity while improving on-target efficacy. </p>
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Toward a drug delivery coating for intraocular lenses
… infection and inflammation, using small molecule pharmaceutics is described. The power, versatility, and utility of this multi-functional system were highlighted by the creation of functional drug coatings on intraocular lenses, bandage, and sutures. These combination devices effectively prevented …
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Bioactivity evaluation of peptide QUB-1480 from the skin secretion of the Green Cascade frog (Odorrana livida)
… QUB-1480 could also be tested in vivo via some pharmaceutics. Meanwhile, QUB-1480 could be combined with other antimicrobial or anticancer agents to be used in the clinical therapy. Because of the inhibitory activity against E. coli, QUB-1480 is expected to lower the dose of the antibiotics to a …
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Automated microreactor system for reaction development and online optimization of chemical processes
… reactions that are common in fine chemical and pharmaceutics is a difficult and expensive task. Because syntheses in these fields have multiple reaction pathways, a significant number of experiments are required to determine the conditions that maximize the yield of the desired product. With few …
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Formation of nanoemulsions and entrapped microdroplets
… personal care, advanced material synthesis and pharmaceutics. They possess attractive properties such as high surface area, robust stability and tunable rheology. There are two broad categories of method to prepare nanoemulsions: high energy and low energy methods. The literature lacks a …
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Application of Fluid Flow for Functional Tissue Engineering of Bone Marrow Stromal Cells
… bone graft composed of a biomaterial scaffold, pharmaceutics, and osteoprogenitor cells. One source of osteoprogenitor cells is bone marrow stroma, which can be obtained from the patient - minimizing the risk of an immune response - directed in vitro to proliferate, and differentiate into a …
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Optically pure D (-) lactic acid biosynthesis from diverse renewable biomass: microbial strain development and bioprocess analysis
… history and wide applications in food, polymer, pharmaceutics and cosmetic industries. Lactic acid has two optical isomers; namely D-lactic acid and L-lactic acid. Racemic mixture of lactic acid are usually used as preservatives and ingredients in solvents, or as precursors for different …
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Influence of hydrophobically modified polyelectrolytes on nanoparticle synthesis in self-organized systems and in water
… (nanotechnology, electrooptical devices, pharmaceutics, etc). The interest derives from the well-known fact that properties of advanced materials are critically dependent on the microstructure of the sample. Control of size, size distribution and morphology of the individual grains or …
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CHITOSAN PARTICLES FOR THE CONTROLLED RELEASE OF PROTEINS
… microparticles found a lot of applications in pharmaceutics such as vaccine delivery, mucosal delivery and gene delivery, etc. Down to the nanoscale, chitosan nanoparticles have more attractive properties more than that of chitosan microparticles, which further widen the applications of …
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