Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 603 for “"Pharmaceuticals"”.
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Application of raman spectroscopy in pharmaceuticals
Experimental research on the use of Raman spectroscopy as an in- and on-line sensing tool and a complementary characterization technique for pharmaceutical applications is presented in this thesis. In the first chapter following a broad overview, the use of Raman spectroscopy, together with x-ray …
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Methods for removing pharmaceuticals from human urine
… of urine are micropollutants such as pharmaceuticals. Pharmaceuticals pose a challenge for the reuse of urine because fertilizers are required to be free of pharmaceuticals. Therefore, the aim of this work was to find a method for pharmaceutical removal from fresh human urine, while …
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Oxidation of methionine residues in protein pharmaceuticals
(cont.) of free methionine. Therefore, the environments surrounding different methionine sites in G-CSF mainly provide spatial restriction to the access to the solvent but do not affect oxidation in a specific manner, consistent with the good correlation between 2SWCN's and the rates of oxidation. …
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Pharmaceuticals removal in soil following wastewater land application
Pharmaceuticals and Personal Care Products (PPCPs) are used worldwide and enter the environment via wastewater treatment system effluent discharges. With increasing concern in water reuse, attention is turning to the wastewater resulting in detection of these compounds in several environmental …
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Understanding Manufacturer-Sponsored Copay Assistance Programs For Pharmaceuticals
Manufacturer-sponsored copay assistance is an increasingly common and controversial practice in the US prescription drug industry. While manufacturers claim that their "copay coupons" help underinsured patients access valuable therapies, insurers are concerned that the discounts undermine …
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Essays on Human Capital Investments: Pharmaceuticals and Education
… than natives to access standard preventive pharmaceuticals for cardiovascular diseases, this may relate to and reinforce the observed health differences between the groups. The fourth essay follows individuals, who were diagnosed with type 1 diabetes onset at age 17 to 20, in order to …
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The business case for continuous manufacturing of pharmaceuticals
Manufacturing in the pharmaceutical industry is presently characterized as a batch production system, which has existed in its current form for decades. This structure is the result of historical regulatory policy as well as the conservative nature of the industry. Recent clarification by US and …
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Pharmaceuticals in the Environment: Assessing Potential Risks to Fish
The widespread presence of human pharmaceuticals in aquatic ecosystems potentially poses a significant threat to vulnerable organisms, such as fish. To address this issue, the environmental risk assessment (ERA) of active pharmaceutical ingredients (APIs) is now integrated into various regulatory …
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Patterns and determinants of Australia's international trade in pharmaceuticals
… of Australia's international trade in pharmaceuticals during the period 1975 to 1992. The thesis provides a thorough review of the theories, measurements and determinants of international trade. Thus, the thesis synthesises the theoretical framework and econometric methodology for …
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An alternative path to physical form generation in pharmaceuticals
Six novel forms of carbamazepine (CBZ) were prepared and characterised by single crystal X-ray diffraction (SXD) and powder X-ray diffraction (PXRD). These were [CBZ(H)][Cl] form I, [CBZ(H)][Cl] form II, [CBZ(H)[Br] form I, [CBZ(H)][Br] form II, [CBZ(H)][Br].H₂O and CBZ₂.[H₃O][Cl].2H₂O. In five of …
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Studies of impurities in crystalline pharmaceuticals and related compounds
… Chapter one provides a summary of impurities in pharmaceuticals, the methods by which they incorporate into host crystals and different methods by which impurities are removed from drug products in the pharmaceutical industry. Background into crystal structure, crystal morphology and polymorphism …
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Understanding the impacts of antipsychotic pharmaceuticals on behaviour in fish
… population, expanded market access, advances in pharmaceuticals, and broadening therapeutic applications, active pharmaceutical ingredients (APIs) are increasingly detected in environmental matrices. APIs enter the environment predominantly via treated and untreated wastewater sources, resulting …
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Engineering of composite pharmaceuticals with improved physicochemical and mechanical properties
Tabletting by direct compression (DC) is the preferred method of tabletting as compared to granulation techniques because among other benefits it is simple, quick, and cost-effective. However, most pharmaceutical powders are not compressible via DC due to poor flowability, compactibility, …
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Environmental risk assessment and human pharmaceuticals: limitations and future improvements
A cocktail of human pharmaceuticals contaminate surface waters worldwide in the ng-μgl-1 range. Adverse effects on non target organisms including endocrine disruption and alterations in behaviour and growth have been reported. All new pharmaceuticals require an environmental risk assessment (ERA) …
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The Removal of Pharmaceuticals from Wastewater by Wet-Air Oxidation
<p>The ubiquitous occurrence of pharmaceuticals and personal care products (PPCPs) in aquatic environments has raised concerns about potential adverse effects on aquatic ecology and human health. Certain pharmaceuticals have recently become a major focus of research to better understand the routes …
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Market, Medicine, and Empire: Hoshi Pharmaceuticals in the Interwar Years
… and empire through a close study of Hoshi Pharmaceuticals during the interwar years. As one of the leading drug companies in East Asia at the time, Hoshi embodied Japan's imperial aspirations, rapid industrial development, and burgeoning consumer culture. The company attempted to control …
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Novel methods and syntheses toward HIV/AIDS and tuberculosis pharmaceuticals
[chemical formula] Described herein is a novel Lewis acid catalyzed rearrangement-coupling of oxygen heterocycles and bis(diethylamino)chlorophosphine that provides direct formation of the phosphonomethyl ether functionality found in several important antiretroviral agents. A wide range of …
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Pharmaceuticals in industrial wastewater and their removal using photo-Fenton’s oxidation
… themselves can contribute to the levels of pharmaceuticals in the environment. This project is based on both the detection and removal of pharmaceuticals from industrial sources. A SPE-LC-MS/MS method for the detection of famotidine, tamsulosin hydrochloride and solifenacin succinate in …
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