Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 693 for “"Pharmaceutical sciences"”.
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Protein production and applications of NMR in pharmaceutical sciences
… The objective of Part II (Applications of NMR in pharmaceutical sciences) is to apply NMR techniques in pharmaceutical sciences. In chapter 7, a rapid, specific, and direct method for the real-‐time quantification of in vitro tenofovir (TNF) release from pH-‐sensitive microparticles using a …
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OPPORTUNITIES AND CHALLENGES OF BIOCATALYSIS IN PHARMACEUTICAL SCIENCES: DEVELOPING TAILORED BIOCATALYSTS FOR SYNTHETIC APPLICATIONS
… in the preparation of stereochemically complex pharmaceutical intermediates. This doctoral research focuses on the development of tailored biocatalysts, specifically amine transaminases (ATAs), for the synthesis of pharmaceutically relevant compounds. To overcome typical limitations of wild-type …
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An Examination of Factors That Influence the Program Choice of Graduate Students in the Pharmaceutical Sciences.
… to: 1) identify factors considered important by pharmaceutical sciences graduate students during the application and acceptance phases of the admission process; 2) identify differences in the evaluative criteria for the two admission phases and for international and domestic students and 3) …
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Desymmetrilizing Organic Molecules via Structural Functionalization
… attracted much attention in research labs and pharmaceutical industry. Particularly, those associated with asymmetric catalysis are actively pursued and published in nearly all organic related journals widely. Obviously, desymmetrization chemistry can serve as powerful tools for many important …
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The Role of B-Arrestin in Agonish-Induced Down-Regulation of the M1 mAChR
Wilham, Laura E., M.S., December 2006 Pharmaceutical Sciences THE ROLE OF â–ARRESTIN IN AGONIST-INDUCED DOWN-REGULATION OF THE M1 mAChR Chair: Darrell A. Jackson G protein-coupled receptors (GPCRs) are the largest family of integral membrane receptors. They mediate diverse cell signaling pathways …
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The Role of B-Arrestin in Agonish-Induced Down-Regulation of the M1 mAChR
Wilham, Laura E., M.S., December 2006 Pharmaceutical Sciences THE ROLE OF â–ARRESTIN IN AGONIST-INDUCED DOWN-REGULATION OF THE M1 mAChR Chair: Darrell A. Jackson G protein-coupled receptors (GPCRs) are the largest family of integral membrane receptors. They mediate diverse cell signaling pathways …
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Investigations in molecular structure: from scattering to molecular complexes of brominated compounds
… was carried out at the Department of Pharmaceutical Sciences at the University of Strathclyde and also at the central synchrotron facility of Station 2.1 at the SRS Daresbury. Small angle X-ray scattering (SAXS) was carried out on solutions of methyl-4-hydroxybenzoate (pMHB) and …
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Scientific communication, information flows in industry - exemplified by pharmaceutical information in China & the UK
… flows in China and the UK with the example of pharmaceutical information. The general objective is to explore the relationship between information situation and the status of science and industry in a country. In China scientific information has long dominated information flows while in the UK …
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Perfil enteroparasitológico dos pacientes atendidos no ambulatório do Hospital Universitário Lauro Wanderley de acordo com as condições climáticas.
… of Clinical Parasitolo gy from the Department of Pharmaceutical Sciences at the Universidade Federal da Paraíba. For these analyses were employded the techniques of Hoffmann and Blagg. In the sample , it was found that 52.5% of the investigated individuals harboring at least one species of …
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Towards Data-driven Development of Advanced Drug Formulations Leveraging Machine Learning and Experimental Automation
… experiments. More recently, its application in pharmaceutical sciences has shown promise in addressing similar challenges.This thesis aims to integrate ML into formulation development to accelerate the process of moving drugs from the bench to bedside. This work has included the development of …
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Deconstructing the mole: a sociological narrative study that explores the mole concept experiences of science students and lecturers, in the context of social justice
… biology, human nutrition, cancer immunotherapy & pharmaceutical sciences. The three lecturers were all academic doctors with varying mole concept lecturing experiences, including post-doctoral work at Manchester, Oxford and Open Universities respectively. Narrative interviews transcripts were …
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VIRAL SAFETY EVALUATION OF BIOTECHNOLOGY PRODUCTS: DEVELOPMENT AND OPTIMIZATIONOF RELIABLE VIRAL CLEARANCE STRATEGIES
… reproducible, and fully transferable to the biopharmaceutical industry. During the first year, thanks to a structured training period at the Department of Pharmaceutical Sciences (DISFARM), University of Milan, I consolidated essential skills in preparative chromatography and conducted an …
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Adeno-Associated Mediated Transduction of Sensory Epithelia Within the Guinea Pig Cochlea
Rova, Cherokee R. L., M.S., Autumn 2006 Pharmaceutical Sciences Adeno-associated virus mediated transduction of sensory epithelia within the guinea pig cochlea Chairperson: Dr. David J. Poulsen, PhD. Hearing loss is the most common disability of the senses and affects 250 million people worldwide. …
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Adeno-Associated Mediated Transduction of Sensory Epithelia Within the Guinea Pig Cochlea
Rova, Cherokee R. L., M.S., Autumn 2006 Pharmaceutical Sciences Adeno-associated virus mediated transduction of sensory epithelia within the guinea pig cochlea Chairperson: Dr. David J. Poulsen, PhD. Hearing loss is the most common disability of the senses and affects 250 million people worldwide. …
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Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor
<p>Hall, Brian, Ph.D., May 2008 Pharmacology/Pharmaceutical Sciences</p> <p> Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor</p> <p>Chairperson: Dr. Keith Parker </p> <p> The human (H) serotonin (5-hydroxytrptamine; 5HT) 1a receptor (R) has been implicated …
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Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor
<p>Hall, Brian, Ph.D., May 2008 Pharmacology/Pharmaceutical Sciences</p> <p> Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor</p> <p>Chairperson: Dr. Keith Parker </p> <p> The human (H) serotonin (5-hydroxytrptamine; 5HT) 1a receptor (R) has been implicated …
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Progress Towards Understanding Of Mechanisms Of Action Of Potent Multifunctional Disease Modifying Therapeutics For Parkinson's Disease & Investigating The Methamphetamine-Induced Striatal Microglia Activation.
… <p>Advisor: Dr. Aloke Dutta</p> <p>Major: Pharmaceutical Sciences</p> <p>Degree: Doctor of Philosophy</p> <p>Our long term goal is to design and develop potent multifunctional disease modifying therapeutics for Parkinson's disease. The objective of my dissertation was to understand the …
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Mechanisms Of Cytokine-Induced Metabolic Dysfunction Of The Pancreatic Beta-Cell
… <p>Advisor: Dr. Anjaneyulu Kowluru</p> <p>Major: Pharmaceutical Sciences</p> <p>Degree: Doctor of Philosophy</p> <p>Type I diabetes is characterized by an absolute insulin deficiency due to loss of pancreatic â-cell mass by autoimmune aggression. During the progression of the disease …
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The rational design of drug crystals to facilitate particle size reduction. Investigation of crystallisation conditions and crystal properties to enable optimised particle processing and comminution.
Micronisation of active pharmaceutical ingredients (APIs) to achieve desirable quality attributes for formulation preparation and drug delivery remains a major challenge in the pharmaceutical sciences. It is therefore important that the relationships between crystal structure, the mechanical …
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Implementation of Solution and Solid Sate Nuclear Magnetic Resonance (NMR) Spectroscopic Techniques for Quantitative and Qualitative Analysis of Molecular Species
… of solution state NMR spectroscopy in pharmaceutical sciences) is to apply NMR techniques in different pharmaceutical projects. In chapter3, a real-time quantification of in vitro Bortezomib (BTZ) release from alginate microparticles using a solution state quantitative boron nuclear …
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