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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 131 for “"Phages"”.
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Propionibacterium acnes and its phages
… by specific bacterial viruses, eg. bacteriophages. If those can contribute to the progress of the diseases mentioned is unknown. In this thesis we have investigated the role of P. acnes as both a pathogen and a commensal, and characterized the phages infecting P. acnes. To undertake those …
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Monitoring lactococcal phages during milk fermentation
… lineages in Blend X. The presence of lactococcal phages in the fermentation industry can have detrimental effect on both the acidification capacity and the quality of the final product. Blend X is employed in many production plants around Europe; therefore, it is not unusual for the blend to …
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Comparative Analysis of Flagellotropic Agrobacterium Phages
The planetary microbiome is dominated by bacteriophages, the viruses of bacteria. Bacteriophages utilize various means to infect their bacterial hosts, but all phages require receptors on the host surface. Flagellotropic bacteriophages involve an actively rotating bacterial flagellum to attach and …
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Understanding the role of phages in the mammalian gut microbiome
… studies were conducted to elucidate the role of phages within the gut microbiome and their impact on host health. The significance of phage in the gut microbiota remains poorly understood due, in part, to the absence of an animal model that allows for a comparative study of conditions with or …
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Investigating Genetic (IN)Compatibility Between Temperate Phages and CRISPR-CAS Systems in Staphylococcus Aureus
… of bacterial DNA viruses, known as temperate phages, which cause both harmful (lytic) and benign (lysogenic) infections under different conditions. Initial studies investigating prokaryotic CRISPR-Cas immunity seemed to indicate that functional, DNA-targeting systems cannot stably co-exist …
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Bacteriophages and their hosts: an investigation into veterinary Pseudomonas aeruginosa strains and the phages isolated against them
… involves a collection of diverse bacteriophages, to reduce the risks of the bacteria developing resistance, as well as bacteriophages with broad host ranges, to ensure that they can clear the target infection. Therefore, bacteriophages (n = 45) were isolated from various natural …
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Molecular analysis of temperate phages in Salmonella enterica serovar Typhimurium DT 64 isolated in Australia / Princess Tlou Mmolawa.
Files on accompanying CD-ROM: Appendix III Phages ST64T and ST64B sequences, are in rtf format.
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Bacteriophages in the honey bee gut and amphibian skin microbiomes: investigating the interactions between phages and their bacterial hosts
… viruses that target bacteria, called bacteriophages (phages), may also shape the animal microbiome. Most phage lifecycles can be classified as either lytic or temperate. Lytic phages infect and directly kill bacterial hosts and can directly regulate bacterial population size. Temperate phages, …
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Effects of cell growth and a mobile genetic element on propagation of the phages SP16 and SP-beta in Bacillus subtilis
Two studies were performed on Bacillus subtilis phages SP16 and SP-beta to characterize the effects of growth and an integrative conjugative element, ICEBs1, respectively. I found that B. subtilis strains are significantly more susceptible to SP16 infection early in the growth phase and less …
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Isolation and Characterisation of Novel Environmental Bacteriophages Which Target the Escherichia coli LamB Outer Membrane Protein
Bacteriophages are viruses which infect bacteria specifically. Over the past decades, phage λ has been extensively studied, especially its interaction with the Escherichia coli LamB (EcLamB) protein receptor. Nonetheless, despite the enormous numbers and near-ubiquity of environmental phages, aside …
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Unraveling the Eco-Evolutionary Complexity of Uncultivated Bacteriophages in the Biosphere
Bacteriophages, or phages, have historically been distinguished by their small sizes and relatively simple genomes compared to cellular life. Discoveries over recent decades, however, have uncovered remarkably large phages, called jumbo phages, which are defined by having genomes over 200 kilobases …
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Characterisation of bacteriophage dynamics associated with foodborne pathogens
Bacteriophages (phages) are viruses that infect bacteria and are found in high abundance in the gut. As antimicrobial resistance rises and interest in microbiome-targeted therapies grows, phages have emerged as potential tools for precisely modulating microbial communities and treating infections. …
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Isolation and Characterization of Bacteriophages Targeting Uropathogenic E. coli
… on the health care system worldwide. Bacteriophages (phages) that target E. coli strains could provide an alternative treatment for UTIs, particularly those resistant to antibiotics. This study aimed to screen a variety of environmental samples for phages that target a UPEC strains and …
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Understanding and exploiting bacteriophage-host interactions for the control and detection of listeria monocytogenes
The hypothesis of this thesis is that phages isolated from the environment can play a role in the future to reduce outbreaks of the disease listeriosis by applying phages as biocontrol agents against the pathogen L. monocytogenes and by incorporating phages into systems for the detection of this …
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Characterisation of the temperate bacteriophages of salmonella enterica and salmonella bongori
… be made that infections of isolates by temperate phages may play a significant role in Salmonella evolution and differentiation. Indeed, it has been suggested that a variable assortment of prophages provides a transferable repertoire of pathogenic determinants in Salmonella. The temperate phages …
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Isolation, Characterisation and Preservation of Bacteriophages for Use in Treatment of Aeromonas hydrophila Infection In Finfish
… infections in the aquaculture sector. Bacteriophages (phages) demonstrated promising results as therapeutic tools, for the effective control of bacterial diseases in aquaculture, as well as in other production animals, companion animals and humans. In the present study, a range of …
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Environmental bacteriophages infecting Dickeya and Serratia species: receptors and diversity
… has generated interest in the use of bacteriophages (phages) as a novel tool for biocontrol. In the last decade, six phages have been isolated in Belgium and Poland using Dickeya solani as the host. Previous work in this laboratory has isolated ninety phages capable of infecting D. solani. The …
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Mapping the Major Epitope(s) of the Glycoprotein of Ebolavirus with QB Phage Display System
… readthrough minor coat protein. The recombinant phages would then be utilized to analyze their antigenicity and to map the major epitope(s) of the glycoprotein determinants. This research study represents a proof of concept and will serve as a guide as to how to produce recombinant phages bearing …
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Integrative Analysis of the Human Gut Phageome Using a Metagenomics Approach
Bacteriophages (or phages; viruses that infect bacteria and archaea) profoundly influence microbial communities. Given the impact of the gut microbiome composition and function on human health, there is a growing focus on phages that inhabit the gut ecosystem. However, the extent of viral …
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Isolation and Characterization of Bacteriophages Infecting Enterobacter cloacae to Reduce Bloater Defect in Cucumber Fermentations
… preventative methods are needed. Bacteriophages (phages) are highly host-specific bacteria killers. Use of phages to control unwanted bacteria in foods is a promising approach because phages do not change food properties. The goals of this research were to isolate, characterize, and …
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