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Showing 1 to 3 of 3 for “"Pflanzenzellkulturen"”.
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Einsatz von Pflanzenzellkulturen als industriell nutzbare Expressionssysteme für therapeutische Proteine
Within the present thesis transgenic BY-2 cultures should be tested regarding their potential as industrial expression system for therapeutic proteins. For this purpose, BY-2 cultures expressing recombinant HSA under control of the CaMV 35SS promoter were developed. A leader peptide ensured the …
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Metabolismus von 14 C-Methoxychlor in humanen P450- transgenen und nicht-transgenen Pflanzenzellkulturen zur Produktion endokrin-wirksamer Metaboliten sowie deren Untersuchung auf östrogene Wirkung
Using the estrogenic organochlor insecticide 14C-methoxychlor, the utility of (P450) transgenic plant cell suspension cultures for the determination of the biotransformation of environmental pollutants was investigated in the present study. Research focus was on turnover rates, metabolic profiles …
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Studien zum Metabolismus von Pestiziden und Xenobiotika durch humane Cytochrom-P450-Monooxygenasen in transgenen Tabakzellkulturen
Detailed data on the metabolism of pesticides in plants is required for registration, therefore several in vitro systems have been developed to generate and identify a broad spectrum of possible metabolites. Therefore transgenic plant cell cultures with the human isoenzymes CYP1A1 and CYP1A2 were …