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Showing 1 to 20 of 71 for “"Pertussis"”.

  1. Comparative proteomic analysis of Australian epidemic Bordetella pertussis

    Bordetella pertussis causes whooping cough, a re-emerging vaccine preventable disease. Pathogen adaptation is an important factor for re-emergence. Since acellular vaccine (ACV) introduction, the predominant strains changed to single nucleotide polymorphism (SNP) cluster I (ptxP3/prn2) from cluster …

    unsw Repository record for Comparative proteomic analysis of Australian epidemic Bordetella pertussis (opens in a new tab)

  2. Pertussis: Advances in Vaccine Development and Disease Control Strategies

    Pertussis, also known as whooping cough, caused by Bordetella pertussis, remains a significant public health challenge despite widespread vaccination programs. This thesis explores advancements in vaccine development and disease control strategies. It emphasizes virulence factors such as Vag8, …

    charles-prague Repository record for Pertussis: Advances in Vaccine Development and Disease Control Strategies (opens in a new tab)

  3. Characterisation and secretion mechanism of Bordetella pertussis autotransporter proteins

    … of new virulence determinants of 5. pertussis is providing important information for understanding the colonisation and survival strategies of the microorganism. B. pertussis deploys a range of surface-associated components to enable its successful colonisation of the host. Bap-5 has …

    glasgow Repository record for Characterisation and secretion mechanism of Bordetella pertussis autotransporter proteins (opens in a new tab)

  4. Investigations into the immunology, physiology and epidemiology of pertussis

    … volume contains an introduction to the topic of pertussis followed by twelve papers on pertussis arising from research conducted while I was a research fellow at St. George's Hospital Medical School from 1985 to 1988. Paper 1 provides a qualitative description of the serum antibody responses to …

    auckland-ms Repository record for Investigations into the immunology, physiology and epidemiology of pertussis (opens in a new tab)

  5. Global dynamics of Bordetella pertussis and implications for control

    *Bordetella pertussis* is the main cause of whooping cough, a disease that still infects millions of individuals annually despite widespread vaccination. This is particularly problematic in neonates, where infection can lead to death. Endemicity, subclinical infections and circulation of multiple …

    cambridge Repository record for Global dynamics of Bordetella pertussis and implications for control (opens in a new tab)

  6. Epidemiology of pertussis in children hospitalised with respiratory tract infection

    … of an effective vaccine against Bordetella pertussis substantially reduced the morbidity and mortality from pertussis, however, in the last decade there appears to have been a substantial increase in pertussis cases as reported mainly in high income countries. Although it is believed that …

    cape-town Repository record for Epidemiology of pertussis in children hospitalised with respiratory tract infection (opens in a new tab)

  7. Epidemiology of pertussis in children hospitalised with respiratory tract infection

    … of an effective vaccine against Bordetella pertussis substantially reduced the morbidity and mortality from pertussis, however, in the last decade there appears to have been a substantial increase in pertussis cases as reported mainly in high income countries. Although it is believed that …

    cape-town Repository record for Epidemiology of pertussis in children hospitalised with respiratory tract infection (opens in a new tab)

  8. Tex aus Bordetella pertussis definiert eine neue Familie von Nukleinsäure-Bindeproteinen

    Das Tex Protein aus Bordetella pertussis definiert eine neue Familie hoch konservierter Proteine in Eubakterien. Ursprünglich wurde das tex Gen aufgrund seines Einflusses auf die Toxinexpression in bestimmten regulatorischen Mutanten von B. pertussis gefunden (Fuchs et al. (1996), J Bacteriol 178, …

    wurz-thes Repository record for Tex aus Bordetella pertussis definiert eine neue Familie von Nukleinsäure-Bindeproteinen (opens in a new tab)

  9. Characterisation of the virulence-related, outer-membrane proteins of B. pertussis

    … proteins was in its infancy and the B. pertussis proteins pertactin, BrkA and tracheal colonisation factor (Tcf) had not been recognised as members of this family. However, the sequence similarity between these Bordetella proteins and a number of other proteins from different genera soon …

    glasgow Repository record for Characterisation of the virulence-related, outer-membrane proteins of B. pertussis (opens in a new tab)

  10. Genetic analysis and characterisation of the BapC autotransporter of bordetella pertussis

    … to have a similar mechanism of export. In B. pertussis, the virulence-regulated proteins Pertactin, BrkA, Tcf, and Vag8 have structural homology at their C-termini (30-kDa) and the N-terminal of the mature proteins share structural characteristics such as RGD and SGXG motifs. Recently, another …

    glasgow Repository record for Genetic analysis and characterisation of the BapC autotransporter of bordetella pertussis (opens in a new tab)

  11. Regulation and Effector Function of TH1 and TH2 Cells in Immunity to Bordetella Pertussis

    … of protective efficacy. Traditionally whole cell pertussis vaccines (Pw) have been controlled using the Kendrick test, which measures protection following intracerebral challenge with Bordetella pertussis. However, this test is unsuitable for assessing the potency o f the new acellular pertussis

    maynooth Repository record for Regulation and Effector Function of TH1 and TH2 Cells in Immunity to Bordetella Pertussis (opens in a new tab)

  12. Characterization of the Aspartate Transcarbamoylase that is Found in the pyrBC" Complex of Bordetella Pertussis

    … transcarbamoylase (ATCase) gene from Bordetella pertussis was amplified by PCR and ligated into pT-ADV for expression in Escherichia coli. This particular ATCase (pyrB) was an inactive gene found adjacent to an inactive dihydroorotase (DHOase) gene (pyrC'). This experiment was undertaken to …

    unt Repository record for Characterization of the Aspartate Transcarbamoylase that is Found in the pyrBC" Complex of Bordetella Pertussis (opens in a new tab)

  13. Examining the Implications of a 7th Grade Pertussis Booster Program in the State of Ohio

    … state of Ohio has been witnessing an increase of pertussis incidence over the past few years. This increase could be attributed to better recognition, reporting, and waning vaccine immunity. As a result, Ohio has implemented a vaccine booster program for 7th graders to try to curb the incidence. …

    ohiolink Repository record for Examining the Implications of a 7th Grade Pertussis Booster Program in the State of Ohio (opens in a new tab)

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