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Showing 1 to 3 of 3 for “"Periplasmic superoxide dismutase"”.
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Characterization of the grvA and grvB Anti -Virulence Genes Encoded by the Gifsy-2 and Gifsy -1 Bacteriophages of Salmonella Typhimurium
… of S. typhimurium. The Gifsy-2 phage carries the periplasmic superoxide dismutase gene, sodCI. Using the IVET system, we identified a Salmonella specific gene grvA, a single open reading frame inserted in the opposite orientation in the tail operon of the Gifsy-2 phage. Contrary to classic …
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Survival of Salmonella in the macrophage phagosome
… is the oxidative burst, in which high levels of superoxide are generated within the Salmonella containing vacuole. SodCI, a periplasmic superoxide dismutase, is required to defend Salmonella against phagocytic superoxide. Work from our lab and others has established that SodCI functions to defend …
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Antimicrobial Effectors Act Cooperatively to Stress Salmonella in the Macrophage Phagosome
… macrophages. The bacterium produces two Cu-Zn periplasmic superoxide dismutases, SodCI and SodCII. Although both enzymes are expressed during infection, only SodCI contributes to virulence in the mouse by combating phagocytic superoxide. We have shown that the differential contribution to …