Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Peripheral proteins"”.
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Using molecular dynamics to probe protein conformational transition mechanisms at the membrane surface
… is a vibrant and dynamic ecosystem. Membrane proteins constitute an integral piece of this ecosystem, allowing for communication between the cell and its environment that is necessary for adaptation and robustness of the cell. Often, membrane proteins are expressed in a default inactive state …
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Influence of protein and lipid domains on the structure, fluidity and phase behavior of lipid bilayer membranes
… membrane, which is a heterogeneous matrix of proteins and lipids that provides a barrier between the interior of a cell and its outside environment. Protein and lipid domains in cell membranes can facilitate receptor localization, stabilize membranes, and influence membrane fluidity. In this …
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Atomic-level characterization of protein-lipid interactions using molecular dynamics simulations
Peripheral membrane proteins are structurally diverse proteins that are involved in fundamental cellular processes. Their activity of these proteins is frequently modulated through their interaction with cellular membranes, and as a result techniques to study the interfacial interaction between …
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Spatial and temporal control of lipid-membrane morphology induced by sphingomyelinase
… between lipid membranes and SMase or other peripheral proteins. We report that SMase can induce both a reaction-induced and a solvent-mediated phase transformation, causing switches of three stationary membrane morphologies and multiple-time-domain ceramide generation in model raft membranes.
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Studies on Chloroplast Protein Synthesis In Vivo and In Vitro
… approaches. The site of synthesis of chloroplast proteins was examined to determine how many proteins were synthesized inside the chloroplast. Cells were labeled in vivo with [<sup>35</sup>S]-sulfate in the presence of either. chloroplast or cytoplasmic protein synthesis inhibitors, and …
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Identification and Characterization of Mlp1p and Mlp2p : Molecular Components of Filaments Localized at the Interface between the Nuclear Pore Complex and Nuclear Interior
… aimed at the identification of novel yeast proteins that could be involved in providing such link. The first step of this approach was the development of a large scale enrichment procedure to prepare yeast nuclear envelopes (NEs). These NEs can be stripped of peripheral proteins to produce a …
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Computational investigations of protein dynamics and its implication in cellular functions: two cases on membrane sculpting by protein complexes and molecular origin of Parkinson's disease
Proteins are complex machineries dedicated to drive many functions in eukaryotic cells. In this article, two cases of protein dynamics and their implications to cellular functions are discussed with computational approaches: membrane sculpting by F-BAR domains and transient β-hairpin structure in …
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MODULATION AND INTERACTIONS OF CHARGED BIOMIMETIC MEMBRANES WITH BIVALENT IONS
… structure of mostly phospholipids with embedded proteins. This two-dimensional structure plays many key roles in the life of a cell. Transmembrane proteins, for example, play the role of a gate for different ions (such as Ca2+). Also found are peripheral proteins that are used as enzymes for …