Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 19 of 19 for “"Peripheral arterial disease - PAD"”.
-
Association of baseline sex hormone levels and prevalent and incident peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis
Peripheral arterial disease (PAD) is a progressive disease that affects up to 10% of the population worldwide. The burden of this disease on individuals, health systems, and communities remains high and will likely only increase as our population continues to age. While treatment and prevention …
-
Prevalence of left ventricular hypertrophy in peripheral arterial disease and its relation to blood pressure
… (LVH) inpatients with newly diagnosed peripheral arterial disease (PAD).<br/><br/>Methods: Consecutive patients referred for the first time for assessment of PAD with a history of intermittent claudication and ankle brachial pressure of index of ≤0.9 were recruited. All subjects …
-
Arterial Calcification and the Clinical Implications on Stent Function
For patients with peripheral arterial disease (PAD), endovascular stenting can be a promising therapy that alleviates plaque obstruction and restores blood flow. However, stent fracture is a serious problem and it can lead to vascular complications, including restenosis. Stent fracture can be …
-
Clinical assessment of arterial stiffness
Increased arterial stiffness is associated with ageing, cardiovascular disease diabetes and renal failure. The aims of this thesis were to investigate the reproducibility of a tissue Doppler imaging (TDI) based ultrasound system to calculate indices of arterial stiffness, and to investigate changes …
-
Multimodal imaging monitoring of key physiological changes of peripheral arterial disease
Peripheral Arterial Disease (PAD) limits blood flow to the lower extremities, causes functional impairment, and in extreme cases, can lead to amputation. While PAD is widely studied, there is still a large gap between preclinical research and clinical translation. This is due in part to the lack of …
-
Non-contrast Magnetic Resonance Angiography for Evaluation of Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a major cause of morbidity and mortality in the USA with an estimated prevalence of up to 20% in those over 75 years. Vascular disease and kidney impairment frequently coexist; prevalence of moderate to severe renal dysfunction in PAD patients is estimated at …
-
Allopurinol as a possible oxygen sparing agent during exercise in peripheral arterial disease
Patients with peripheral arterial disease (PAD) can only walk so far before they get leg pain (intermittent claudication) and have to stop. They are also at risk in the future of needing amputation of one of their limbs. Allopurinol is a new possible treatment for this condition as it has been …
-
A multimodal lens into vascular recovery in a preclinical model of peripheral arterial disease
… factors is disrupted, either through injury or disease. Cardiovascular complications are among the leading causes of morbidity and mortality in diabetic patients, and account for over 80\% of diabetes-associated deaths. One of the most serious is peripheral arterial disease (PAD), which is …
-
Multi-modality Imaging to Determine the Role of Calcification and Inflammation on Restenosis Rates Following Lower Limb Angioplasty
Peripheral arterial disease (PAD) is a major cause of CVD-related death and disability. Restenosis is common, occurring in 40-60% of cases at 12 months following lower extremity percutaneous transluminal angioplasty (PTA). No such method exists to identify patients who are at risk from restenosis …
-
A contemporary examination of screening for peripheral arterial disease for the purpose of cardiovascular risk assessment
Peripheral Arterial Disease (PAD) is a marker of systemic atherosclerosis and is associated with a three to six fold increased risk of death from cardiovascular causes. Furthermore, it is typically asymptomatic and under-diagnosed; this has resulted in escalating calls for the instigation of …
-
Outcome of Ischaemic Foot Ulcers in Patients with Diabetes, with or without Revascularization
… was to study patients with diabetes and severe peripheral arterial disease (PAD) in regard to outcomes of foot ulcers, factors related to outcomes, and occurrences of new ulcerations and amputations following healing of the initial ulcer. Patients with diabetes and a foot ulcer, consecutively …
-
A comparative study of home based exercise on symptomatic peripheral arterial disease
Peripheral arterial disease (PAD) is a prevalent atherosclerotic disorder characterised by exertional limb pain, loss of limb and a high mortality rate - those patients with an ABPI of<0.40 have a 5-year probability of survival of only 44%. Intermittent claudication, the exercise-induced ischaemic …
-
Vascular calcification as a risk factor for peripheral arterial disease and its effects on angiogenesis
Peripheral arterial disease (PAD) refers to the obstruction or blockage of arteries of the lower extremity vessels. PAD is characterised by accelerated arterial calcification and impairment in angiogenesis, both of which associate with adverse cardiovascular outcomes. The pathogenesis of lower …
-
Inflammation and haemostasis in the development and progression of peripheral atherosclerotic disease
Peripheral arterial disease (PAD) defines atherosclerotic disease of the arteries to the legs. PAD begins early in life and remains asymptomatic over long periods. The ankle brachial index (ABI) is an important diagnostic test which can identify asymptomatic individuals and serve as a good marker …
-
Metabolic profile and post-operative outcomes in contemporary patients with peripheral arterial disease and critical limb ischaemia
Background: Peripheral arterial disease (PAD) is an established occlusive disease of the peripheral arteries and is not uncommon in the elderly. Atherosclerosis accounts for 90% of the pathology. Only 15% of affected individuals become symptomatic. Most symptomatic individuals present with …
-
Peripheral arterial disease and diabetes: effects on endothelial progenitor cell differentiation and nitric oxide metabolism
In the recent years it is emerged that peripheral arterial disease (PAD) has become a growing health problem in Western countries. This is a progressive manifestation of atherothrombotic vascular disease, which results into the narrowing of the blood vessels of the lower limbs and, as final …
-
Stimulating angiogenesis into biomaterials through the delivery of growth factors
lschemic disease in form of ischemic heart disease (IHD), ischemic stroke and peripheral arterial disease (PAD) due to atherosclerosis represents a massive clinical and economic burden to healthcare and is currently the number one cause of death in the world. Treatment modalities for peripheral …
-
Advances in medical infrared thermography
… great sensitivity. The recent 2019 coronavirus disease (COVID-19) pandemic revealed that disease transmission control is crucial in preventing an outbreak. Thermography has been considered the gold standard for screening fevered individuals during pandemics since the 2003 SARS outbreak. With the …
-
Ενδοαγγειακή απεικόνιση των αγγείων κάτωθεν του βουβωνικού συνδέσμου με Οπτική Συνεκτική Τομογραφία (Optical Coherence Tomography)
… που πάσχουν από περιφερική αρτηριοπάθεια (PAD). Μελετήθηκαν, με ποσοτική ανάλυση του αυλού τους (Quantitative vascular analysis), αρτηρίες με διάμετρο έως 7 χιλιοστά. Μικτά χαρακτηριστικά από περιοχές πλούσιες σε λιπίδια, εναποθέσεις ασβεστίου και ασβεστοποιημένες πλάκες, νεκρωτικές …