Global ETD Search
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Showing 1 to 6 of 6 for “"Perinatal Hypoxia"”.
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Perinatal Hypoxia Exposure on the Developing Heart: The Role of Endothelin-1
… this process may alter cardiomyocyte endowment. Hypoxia/anoxia is a major perinatal stressor that often afflicts the fetus as well as the premature infant, and leads to the production of endothelin-1. Our study aims to test the hypothesis that perinatal hypoxia exposure induces a premature …
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IL-1 activation of NF-kB contributes to perinatal hypoxia/ischemia induced cell death
IL-1 activity has been implicated in perinatal hypoxia/ischemia (HI) brain damage without the underlying mechanisms being characterized. We used a 7-day-old rat model to elucidate the role of NF-kB in HI stimulation of IL-1 signaling. HI was induced by permanent ligation of the left carotid artery …
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Classification of Electroencephalogram in Ovine Model of Perinatal Hypoxia by Movement of the Autoregressive Model Parameters
… encephalopathy (HIE) secondary to perinatal asphyxia occurs when the brain does not receive enough oxygen and blood. Oxygen deprivation can be caused by knotting of the umbilical cord, failure to breathe at birth, as well as a difficult birth. HIE is a dangerous condition that …
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An assessment of the role of Doppler ultrasound velocity waveform analysis of the umbilical artery in the diagnosis of fetal distress in labour
… were carefully examined for clinical signs of perinatal hypoxia. Results: Twenty seven fetuses were followed through labour. No relation was found between umbilical artery Pourcelot ratio (resistance index) on admission in labour and umbilical artery base deficit. Six fetuses were born with an …
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Effect of Maternal Hypoxia on Fetal Development: Programming of HIE Phenotype in Neonatal Rat Brain
… neurobehavioral disorders among others. Maternal hypoxia is one of the most common intrauterine growth restricted environment during pregnancy. Perinatal hypoxic-ischemic encephalopathy is an important cause of brain injury in the newborn due to a systematic asphyxia. Our study aims to test the …
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Perinatal hypoxic-ischemic brain injury – characterization, mechanisms and treatment
… molecular mechanisms underlying the spread of perinatal hypoxic-ischemic brain injury, particularly connexin hemichannels, pannexin channels and purinergic signaling, as well as to identify mechanisms of injury that are poorly attenuated by therapeutic hypothermia in order to find suitable …