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Showing 1 to 4 of 4 for “"Perillyl alcohol"”.
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Characterization of perillyl alcohol as a cell migration-inhibiting compound
… normal and MDA-MB 435 cancerous breast cells. Perillyl alcohol at 0.5 mM inhibited normal breast cell migration while it failed to affect cancer cell migration. Finally, we examined the loss of prenylation of RhoA, a small GTPase protein involved in the formation of focal adhesions and stress …
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The Dietary Isoprenoid Perillyl Alcohol Inhibits Telomerase Activity in Prostate Cancer Cells
… the first evidence that a plant-derived compound–perillyl alcohol regulates telomerase activity via the mammalian target of rapamycin (mTOR) pathway in prostate cancer cells. Telomerase–the enzyme responsible for immortalizing cells through telomeric repeats addition–is de-repressed early in an …
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Perillyl alcohol and perillic acid enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro
Limonene and perillyl alcohol are the naturally occurring monoterpenes found commonly in plant fruits and vegetables. Perillyl alcohol (POH) elicited anticarcinogenic effects in a number of cancer models and pharmacokinetic studies in humans revealed that perillic acid (PA) is the major circulating …
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NON-CONVENTIONAL YEASTS AS CELL FACTORIES: FROM FOOD WASTE TO ADDED-VALUE PRODUCTS.
… a marine yeast strain for the synthesis of perillyl alcohol. In this work, molasses and seawater were used to obtain the biocatalyst biomass employed as whole-cell biocatalysts, which were immobilized in alginate beads to easily scale up the reaction in a rotating bed reactor (SpinChem®). …