Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Perifosine"”.
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VOLUMETRIC GROWTH MODEL OF HUMAN MEDULLOBLASTOMA IN THE NUDE MOUSE CEREBELLUM
… In the orthotopic intracerebellar tumor model, perifosine significantly increased the survival of treated mice while qualitatively reducing leptomeningeal dissemination. In the flank model, perifosine effectively suppressed the volumetric growth, decreased activation of the AKT pathway and …
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Examining the effect of anti-tumor lipid drugs on pH homeostasis and membrane structure in Saccharomyces cerevisiae
… anti-tumor lipids, miltefosine and perifosine, cause PM disorganization in a manner analogous to edelfosine, suggesting a similar mode of action for this drug family.
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Mechanismen der Durchbrechung der sekundären Antiöstrogenresistenz durch GnRH-Analoga in Mammakarzinomzellen
… Zellen mit dem potentiellen Akt-Inhibitor Perifosine. Eine Analyse der Oberflächenrezeptoren von Wachstumsfaktoren mittels Durchflusszytometrie sowie eine Analyse von Mediatoren von Signaltransduktionswegen ergab Hinweise auf die zu Grunde liegenden Resistenzmechanismen, die bei den beiden …