Global ETD Search
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Showing 1 to 2 of 2 for “"Peptide Initiation Factors"”.
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Analysis of the Role of EIF5A in Mammalian Translation
… Analysis of screening data identified eukaryotic initiation factor 5A (EIF5A) as novel regulator of MYC translation. eIF5A is a highly conserved translation factor that has been demonstrated to relieve ribosome pauses during translation elongation at 'difficult to translate' peptide sequences in …
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Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei
… for the (deoxy)hypusination of eukaryotic initiation factor 5A (eIF5A). Hypusination, a post-translational modification, occurs via two enzymatic reactions. First, deoxyhypusine synthase (DHS) transfers the aminobutyl moiety of spermidine onto the eIF5A-lysine generating deoxyhypusine which …