Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Pepd"”.
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Hydrolysis and Toxicity of Aspartyl Peptides and the Influence of Metal Ions on Aspartyl Peptide Hydrolases in Salmonella Enterica Serovar Typhimurium
… for growth on Asp-Leu as a Leu source revealed pepD, pepA, pepE, and pepB . Other strains containing a single peptidase gene were constructed. Extracts from the pepA+, pepB +, pepD+, and dapE + strains all showed activation by Mn2+ for aspartyl peptidase activity. Disruption of Mn2+ transport …
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Towards An Understanding Of The Etiology Of Abdominal Aortic Aneurysms: Identification Of Genes Implicated In Aaa Risk And Development
… positional candidate genes, <em>CEBPG</em>, <em>PEPD</em> and <em>CD22</em>, that had both functions relevant to AAA and expression in AAA tissue exhibited nominal association and further studied by DNA sequencing of exons. Sequence variants were identified in <em>PEPD</em> and <em>CD22</em>, but …
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The role of extracellular matrix remodelling in brown adipose tissue functions: New candidates
… dysfunction; 2) I characterised the impact of Pepd partial ablation (a prolidase involved in the last step of collagen degradation and turnover) in brown adipocytes functions in vitro; 3) I performed a data integration analysis to obtain a list of the most promising ECM-related candidates …
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Investigations into the biosynthesis and mode of action of the phosphonate antibiotic dehydrophos
… quadruple mutants lacking peptidases PepA, PepB, PepD, and PepN. However, reintroduction of any one of these peptidases resulted in restored bioactivity. Following peptidase action the released C-terminal portion of dehydrophos, a phosphonate analogue of dehydroalanine, undergoes a tautomeric …
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The interplay between genes and dietary factors in the aetiology of Type 2 Diabetes Mellitus
… variants in or near TCF7L2, GIPR, CAV2 and PEPD (p<0.05) on T2D. All studies were observational with moderate to serious risk of bias and limitations that included lack of adequate adjustment for confounders, lack of reported replication and insufficient correction for multiple testing. …