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Showing 1 to 20 of 27 for “"PepT1"”.

  1. Regulatory Balance Between the Peptide Trasporter, Pept1, and Amino Acid Transporter Gene Expression in the Enterocyte

    Miller, Carin R.Virginia Tech2012

    … the form of peptides. The peptide transporter, PepT1, is thought to be the major facilitator of peptide transport in the enterocyte. It is unknown if the peptide transporters and free amino acid transporters operate in a compensatory fashion to regulate the amino acid balance within the …

    vt Repository record

  2. Molecular Cloning and Functional Characterization of a Turkey Intestinal Peptide Transporter (tPepT1), and Developmental Regulation of PepT1 Expression in Turkey and Broiler Embryos

    Van, LingVirginia Tech2002

    … a turkey intestinal peptide transporter, tPepT1, was isolated from a turkey small intestinal cDNA library by screening with our chicken PepT1 (cPepT1) cDNA probe. The tPepT1 cDNA is 2,921-bp long and encodes a 79.4 kDa protein of 714 amino acids (AA) with 12 predicted transmembrane domains. …

    vt Repository record

  3. Gene Expression of the Intestinal Peptide Transporter 1 and Peroxisome Proliferator-Activated Receptor alpha Following Fasting/Refeeding and Ligand Administration in Chickens

    Madsen, Sara LindslyVirginia Tech2009

    … acid transporters and the peptide transporter, PepT1. The nuclear receptor PPARα may play a role in the activation of PepT1. The objectives of this study were to evaluate the effect of a fasting/refeeding regimen and gavaging a PPARα ligand on expression of chicken PepT1 and PPARα. During the …

    vt Repository record

  4. Tissue- and Development-specific Expression of Proton-mediated Peptide Transporters in the Developing Chicken

    Zwarycz, BaileyVirginia Tech2012

    PepT1, PepT2 and PHT1 are all members of the proton-coupled oligopeptide transporter family, which are important in the transport of amino acids in peptide form. PepT1 acts as a low affinity/high capacity transporter and PepT2 as a high affinity/low capacity transporter for di- and tri-peptides. …

    vt Repository record

  5. Structure-function studies of SLC15 peptide transporters

    Senan, AnishOxford Brookes University2015

    … (POT) family of proteins includes mammalian PepT1 (SLC15A1; high capacity, low affinity) and PepT2 (SLC15A2; low capacity, high affinity) transporters which are involved in the co-transport of protons and di- and tri- peptides and drugs similar in structure (peptidomimetics). PepT1, and to a …

    oxford-brookes Repository record

  6. Transport and utilization of arginine and arginine-containing peptides by rat alveolar macrophages

    Yang, Xiaodong2019

    … that alveolar macrophages (AM) from rats exhibit pepT1-like transporter for the uptake of small arginine-containing peptides (ACPs) and utilized these peptides as direct substrates for nitric oxide (NO) production.;Method. A HPLC assay was developed for quantitative measurement of Arg and ACPs in …

    wvu Repository record

  7. Ontogeny and biological function of epithelial cells in the chicken yolk sac and small intestine

    Zhang, HaihanVirginia Tech2018

    … the spatial expression of nutrient transporters (PepT1 and SGLT1), intestinal stem cell markers (Lgr5 and Olfm4), and avian beta defensins in the chicken yolk sac and small intestine during the embryonic and early posthatch stages. RNAscope in situ hybridization was used to identify the …

    vt Repository record

  8. Dietary and Developmental Regulation of Nutrient Transporter Gene Expression in the Small Intestine of Two Lines of Broilers

    Gilbert, Elizabeth R.Virginia Tech2008

    … evaluated included the peptide transporter, PepT1, 10 AA transporters (rBAT, bo,+AT, ATBo,+, CAT1, CAT2, LAT1, y+LAT1, y+LAT2, BoAT and EAAT3), four sugar transporters (SGLT1, SGLT5, GLUT5, and GLUT2), and a digestive enzyme, APN. For PepT1, Line B had greater quantities of mRNA compared with …

    vt Repository record

  9. Distribution and Relative Abundance of Nutrient Transporter mRNA in the Gastrointestinal Tract of Black Bears

    Gilbert, Elizabeth R.Virginia Tech2005

    … abundance of mRNA of a peptide transporter (PepT1), a glucose transporter (SGLT1), two AA transporters (NBAT, bo,+AT), and a digestive enzyme, aminopeptidase N (APN), in the intestinal tract of black bears were investigated. Ten bears were used for this study. For tissue collection, the …

    vt Repository record

  10. Cloning, Sequencing and Expression of a Porcine Intestinal Peptide Transporter in a Mammalian Cell Line

    Klang, Judith ElisaVirginia Tech2002

    … as small peptides. A peptide transport protein, PepT1, is responsible for the absorption of intact peptides arising from digestion of dietary proteins. PepT1 is driven by a H+-coupled transport system that allows for the absorption of small peptides through the intestinal brush border membrane. …

    vt Repository record

  11. Molecular Cloning, In Vitro Expression, and Functional Characterization of an Ovine Gastrointestinal Peptide Transporter (oPepT1)

    Pan, YuanXiangVirginia Tech2000

    … characterization of a peptide transporter, oPepT1, from ovine intestine. The ovine intestinal oPepT1 cDNA was 2,829 bp long encoding a protein of 707 amino acid residues with an estimated molecular size of 79 kDa, and a pI of 6.57. The cDNA contained a 79-bp 5' untranslated sequence and a …

    vt Repository record

  12. Developmental Gene Expression in the Small Intestine of Chickens from Lines Divergently Selected for High or Low Juvenile Body Weight

    Miller, Carin R.Virginia Tech2007

    … gene expression of the peptide transporter PepT1, the glutamate/aspartate transporter EAAT3, the sodium-dependent glucose transporter SGLT1, and the fructose transporter GLUT5 in the small intestine of chickens from lines divergently selected for high (HH) or low (LL) eight-week body weight …

    vt Repository record

  13. Developmental Regulation of the Expression of Nutrient Transporter and BrushBorder Membrane Hydrolase Genes in the Small Intestine of Piglets

    Xiao, XunjunVirginia Tech2005

    … transporter (H+-dependent peptide transporter 1, PepT1), four amino acid transporters (excitatory amino acid carrier 1, EAAC1, Na+-dependent neutral amino acid transporter, ATB0, the light chain of a heterodimeric transport system b0,+ involved in the heteroexchange of cationic and neutral amino …

    vt Repository record

  14. The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells

    Heinrich, MarcusUniversität Leipzig

    … mRNA expression of the four known POTs (PEPT1, PEPT2, PHT1, and PHT2) was examined in three glioblastoma cell lines, ten primary tumor cell cultures, in freshly isolated tumor tissue and in healthy brain. Using high-performance liquid chromatography coupled to mass spectrometry, the …

    qucosa-diss

  15. Small Intestinal Transporters in Two Species of Galliformes: Male and Female Turkey (Meleagris gallopavo) and Chicken (Gallus gallus)

    Weintraut, Melodie LynnVirginia Tech2015

    … characterize amino peptidase N (APN), peptide (PepT1), amino acid (ASCT1, bo,+AT, CAT1, EAAT3, LAT1, y+LAT2), and sugar transporter expression (GLUT2, GLUT5, SGLT1) in the small intestine of male and female turkeys. Small intestine samples were collected during embryonic development (E21, E24) …

    vt Repository record

  16. Gene Expression of Nutrient Transporters and Digestive Enzymes in the Yolk Sac Membrane and Small Intestine of the Developing Embryonic Chick

    Speier, Jacqueline S.Virginia Tech2011

    … Genes examined included peptide transporter PepT1, amino acid transporters EAAT3, CAT1, and B0AT, monosaccharide transporters SGLT1 and GLUT5, and digestive enzymes APN and SI. Expression of these genes was measured in YSM at embryonic day (e) 11, 13, 15, 17, 19, 20, and 21 and small …

    vt Repository record

  17. Delayed access to feed affects broiler small intestinal morphology and intestinal cell ontogeny

    Liu, Kuan-LingVirginia Tech2019

    … Marker of Ki-67 (Ki-67), Peptide Transporter 1 (PepT1), and Mucin 2 (Muc2), in response to DAF. The Olfm4 mRNA can clearly identify stem cells in the intestinal crypt, which allows VH and CD to be measured, while Ki-67 marks the proliferating cells. The peptide transporter PepT1 is located on …

    vt Repository record

  18. Short-Chain Fatty Acids and Functional Adaptations in the Neonatal Intestine

    Albin, David MillerUniversity of Illinois at Urbana-Champaign2015

    … addition, studies examining peptide transporter (PepT1) protein indicated that 9Bu induces trafficking of PepT1 to the brush-border membrane. Therefore, Bu enhances intestinal adaptation in a neonatal pig model, probably by increasing transcription of nutrient transporters, as well as increasing …

    uiuc Repository record

  19. Outlining a balance-point model of homeostasis in the small intestine of broiler chickens

    Cloft, Sara E.Virginia Tech2022

    … in the ileum of Peptide Transporter 1 (PepT1) a marker gene for enterocytes and Mucin-2 (Muc2) a marker gene for goblet cells compared to non-injected control embryos. Also, on e20 the embryos in ovo fed saline only had numerically increased PepT1 and Muc2 compared to non-injected …

    vt Repository record

  20. Expression of Digestive Enzymes and Nutrient Transporters in the Intestine of Eimeria-challenged Chickens

    Su, ShengchenVirginia Tech2013

    … APN and SI, peptide and amino acid transporters: Pept1, ASCT1, bo,+AT/rBAT, B0AT, CAT1/2, EAAT3, LAT1 and y+LAT1/2, sugar transporters: GLUT1, GLUT2, GLUT5 and SGLT1, mineral transporter: ZNT1 and an immune factor: LEAP2 in the duodenum, jejunum, ileum and ceca of Eimeria-challenged layers and …

    vt Repository record

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