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Showing 1 to 20 of 184 for “"Penicillin"”.
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Penicillin in acute gonorrhoea
The application of penicillin to the treatment of disease ranks with the improved control of malaria as one of the greatest advances in medicine consolidated during the war years.
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Synthetic studies related to penicillin
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1952.
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The penicillin-binding proteins of Bacilli
A study of the penicillin-binding proteins (PBPs) in the membranes of various species of Bacilli by dodecylsulphate/polyacrylamide gel electrophoresis followed by detection of the PBPs by fluorography has shown the presence of 3-5 such proteins depending on the species. Labelling of growing cells …
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Evaluation of Concentrations in Penicillin Sensitivity Discs
… importance. | Prior to Fleming's discovery of penicillin in 1929, and. its subsequent introduction into clinical use in I9I4-I, there was no need for such tests. Since that time, the number of new antibiotics has been rapidly increasing. The introduction of streptomycin, bacitracin, …
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Metal complexes of penicillin and cephalosporin antibiotics
The interaction between metal-ions and the penicillin and cephalosporin antibiotics have been studied in an attempt to determine both the site and mechanism of this interaction. The solution conformation of the Cu(II) and Mn(II) complexes were determined using an n.m.r, line broadening, technique. …
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Penicillin milk levels in cows following intramammary infusions
Thesis (M.S.)--Michigan State College of Agriculture and Applied Science. Dept. of Surgery and Medicine, 1949
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Improving the identification of a penicillin fermentation model
… of differential equation based models of the penicillin G fermentation. Published penicillin fermentation models have been reviewed and compared with regard to their abilities to predict fermentation behaviour, genetic algorithms have been applied to the design of optimal experiments for model …
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Functional Studies of Penicillin-binding Protein 1 in Bacillus subtilis
The penicillin-binding proteins (PBPs) synthesize and modify peptidoglycan (PG), the main structural element of the bacterial cell wall. PBPs and PG synthesis are highly conserved in all bacteria and both have been important targets for antibiotic and antibacterial development. In the Gram positive …
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Bloat Results From Various Drenchings Including Effectiveness of Penicillin For Prevention
<p>Body conformation is associated with function among all classes of livestock. Dairy cattle type deals with characteristics indicating ability to produce milk and butterfat economically along with breed character and other values of an aesthetic nature. In order to have economical milk and …
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The synthesis of N,N-diacylamino acids and analogs of penicillin
Thesis (Ph.D.) Massachusetts Institute of Technology. Dept. of Chemistry, 1951.
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Characterization of penicillin production by an immobilized biofilm of Penicillium chrysogenum
… slab geometry was characterized with respect to penicillin production at various sugar and oxygen concentrations by studies using a novel bench scale bioreactor. The biofilm was submerged in aerated liquid media, mounted vertically in a tube and oriented so that the liquid media and sparged gas …
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An investigation of intraperitoneal procaine penicillin G administration in lactating dairy cows
… the pharmacokinetic profile of procaine penicillin G after intraperitoneal (IP) administration in 8 lactating dairy cows. Procaine pencillin G (PPG, 21,000 IU/kg) was deposited into the abdominal cavity of each cow following an incision in the right paralumbar fossa. Blood and milk …
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Requirements for Compartmentalization of Penicillin-Binding Proteins during Sporulation in Bacillus subtilis
Penicillin-binding proteins (PBP's) are membrane-associated enzymes involved in the polymerization of peptidoglycan. PBP's are divided into three classes based upon their molecular weights and functional domains. Gene expression is regulated in the two differentiated cells in Bacillus subtilis, the …
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Studies of the Class A High-Molecular Weight Penicillin-Binding Proteins in Bacillus subtilis
… bacterial cell wall. These proteins, known as penicillin-binding proteins (PBPs), are identified through the presence of conserved motifs within their functional domains. The Class A high-molecular weight PBPs are bifunctional, performing the penicillin-sensitive transpeptidase activity and the …
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Mode of Action of Penicillin in Pneumococci: From Inhibition of Cellular Targets to Bacterial Death
… inhibition of these targets (the membrane bound penicillin-binding proteins, or PBPs) leads to the irreversible antibacterial effects of these drugs have remained elusive. Treatment of Streptococcus pneumoniae with penicillin (or other cell wall inhibitors) results in a rapid sequence of events …
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Characterization of two Bacillus subtilis penicillin-binding protein-coding genes, ykuA (pbpH) and yrrR (pbpI)
Penicillin-binding proteins (PBPs) are required in the synthesis of the cell wall of bacteria. In Bacillus subtilis, PBPs play important roles in the life cycle, including both vegetative growth and sporulation, and contribute to the formation of the different structures of vegetative cell wall and …
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