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Showing 1 to 6 of 6 for “"Pediatric brain tumors"”.
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Survivors Of Pediatric Brain Tumors: Psychosocial Outcomes And Executive Function
Children treated with CNS-directed therapy for brain tumor (BT) are at significant risk for developing late effects secondary to both disease and treatment. Executive functions (EF) encompass those skills necessary for appropriate problem solving and other goal-directed behaviors. Although no …
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Patient-derived and xenograft-derived organoids for characterization, drugs testing and biobanking of pediatric brain tumors
Central nervous system (CNS) tumors are the most common solid tumors in the pediatric population and the leading cause of death among childhood cancers. They present common features related to the development and produce symptoms based on their location, rate of tumor growth and age of the child. …
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Radiation therapy of pediatric brain tumors : comparison of long-term health effects and costs between proton therapy and IMRT
Radiation therapy is an important component of pediatric brain tumor treatment. However, radiation-induced damage can lead to adverse long-term health effects. Proton therapy has the ability to reduce the dose delivered to healthy tissue when compared to photon radiation therapy, but this dose …
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Characterization of brain response following cranial radiotherapy
… (CRT) is a vital component for the treatment of pediatric brain tumors, with combination therapy that includes CRT resulting in almost 90\% five-year survival. However, survivors treated with CRT exhibit alterations in brain development and long-term deficits in brain structure and function. …
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Fine Motor Skills, Processing Speed, And White Matter Integrity Among Pediatric Brain Tumor Survivors Who Received Proton Radiotherapy
Pediatric brain tumors are among the most common cancers of childhood. As survival rates have improved, the emphasis among medical professionals has shifted from mere survival to maximizing quality of life. A conventional method of treatment, photon radiotherapy (XRT), subjects healthy brain tissue …
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A Novel Biomaterial Enables Chemotactic Study of Motile Central Nervous System-derived Tumor Cells
… (MB) is one of the most common, malignant pediatric brain tumors worldwide [61]. It is characterized by high tumor invasiveness to extraneural tissues and reoccurrence in the cerebellum after total resection [2]. In the case of MBs, the migration of cells from primary tumors to other …