Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Pathological Conditions, Signs and Symptoms"”.
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Immune Recognition of Self Nucleic Acids Driven By Endogenous Antimicrobial Peptides: Role In Autoimmunity
… of extracellular host-derived self-DNA and self-RNA is prevented by endosomal seclusion of the Toll-like receptors (TLRs) in the dendritic cells (DCs). However, in psoriasis plasmacytoid dendritic cells have been found to be able to sense self-DNA molecules in complex with the endogenous …
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Machine Learning Classification of Traumatic Brain Injury Patients Versus Healthy Controls Using Arterial Spin Labeled Perfusion MRI
… (TBI) is one of the most common causes of death and disability worldwide, yet accurate<em> in vivo</em> detection of TBI neuropathology remains challenging due to complexities in the structural and functional changes observed post-injury as well as limitations in conventional neuroimaging …
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Applications of Causal Inference Methods for the Estimation of Effects of Bone Marrow Transplant and Prescription Drugs on Survival of Aplastic Anemia Patients
… Each paper contributes to a nuanced understanding of treatment impacts, specifically focusing on bone marrow transplantation (BMT) and prescription drugs, and the identification of optimal treatment strategies.</p> <p>The first paper, "Causal Inference Analysis for Assessing the Effect of …
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Behavioral Insights Into Nociceptor Function: A Systematic Approach to Understanding Postsurgical and Neuropathic Pain Mechanisms In Rats
<p>Postsurgical and neuropathic pain are each clinically common, and often associated with ongoing pain. Ongoing pain has been linked to ongoing activity (OA) in human C-fiber nociceptors. Preclinical studies using rodent neuropathic models have concentrated on allodynia driven by OA generated in …
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Identifying a Glucocorticoid-activated GPCR that Rapidly and Non-Genomically Increases cAMP Levels in Mammalian Cells
… may be explained by receptor desensitization and/or the presence of a neutrophilic endotype. One understudied phenomenon of GCs is their ability to induce rapid, non-genomic actions. For example, GCs can acutely modulate calcium concentrations levels, induce smooth muscle relaxation and …