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Showing 1 to 20 of 517 for “"Pathogenicity"”.
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Pathogenicity of Murine Cytomegalovirus Mutants
<p>The purpose of this study was to identified nonessential murine cytomegalovirus (MCMV) genes involved in pathogenesis in vivo. Our approach to identifyjng these genes consisted of constructing MCMV mutants, and then analyzing these mutants in vitro and in vivo. Recombinant viruses (RV) …
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Formation and Pathogenicity of Cytotoxic Curli Intermediates
… coli. Here, we investigate the formation and pathogenicity of cytotoxic curli intermediates previously unidentified in the in vitro biofilm. The identification of multiple curli conformations within the biofilm biogenesis aides in the understanding of amyloid kinetics in the enteric biofilm. …
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Aging Exacerbates Neutrophil Pathogenicity In Ischemic Stroke
<p>Ischemic stroke is a major cause of disability and mortality worldwide. As most patients cannot receive the currently approved therapies for ischemic stroke, novel treatments are critically needed. Cerebral ischemia causes irreversible tissue damage, referred to as the “tissue core”, which is …
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The Morphology and Pathogenicity of Leptodiscus Terrestris
Made available in DSpace on 2014-12-05T20:30:09Z (GMT). No. of bitstreams: 1 5902037.pdf: 4039651 bytes, checksum: 60e4dd108324abba478cf3b0fe465fbd (MD5) Previous issue date: 1959
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Pathogenicity Genes of Pseudomonas Syringae Pv. Tabaci Br2
Pseudomonas syringae pv. tabaci BR2 produces tabtoxin and causes wildfire disease on tobacco and bean plants. Tn5 mutants of PTBR2.024 were generated by using pGS9::Tn5. The Tn5 mutants wre prototrophs, resistant to kanamycin, nalidixic acid, and streptomycin, but sensitive to chloramphenicol. …
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Elucidating three novel mechanisms of Pseudomonas syringae pathogenicity
… (chemical-directed movement) in P. syringae pathogenicity. Not only is chemotaxis required for pathogenicity of P. syringae on plants, but it also appears to contribute to delimiting the host range of several P. syringae pathovars. These results highlight that additional aspects of P. …
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Pathogenicity and selective constraint in the non-coding genome
Gene regulation plays a central role in evolution, organismal development, and disease. Despite the critical importance of gene regulation throughout development, there have been few genetic variants in regulatory elements with large effects that have been robustly associated to disease. In this …
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Evolution of a gene for pathogenicity: endo-pectate lyase
Erwinia carotovora subsp. Carotovora (Ecc) and Erwinia carotovora subsp. Atroseptica (Eca) are plant pathogenic bacteria that cause soft rot disease of many plant species and blackleg disease of potatoes, respectively. Ecc and Eca attack plants by means of a group of extracellular plant …
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Th17 Cell Pathogenicity Promoted by Integrin α3 During Autoimmune Neuroinflammation
… α3 as a Th17 cell-selective determinant of pathogenicity in experimental autoimmune encephalomyelitis, a mouse model of MS. CNS-infiltrating Th17 cells express high integrin α3, the expression of which is induced by transcription factors that are required for Th17 cell specification. The …
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Genetics of pathogenicity in flax rust / by Gregory J. Lawrence
Typescript (photocopy)
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Xanthomonas campestris pv. glycines: Pathogenicity genes, races, and soybean yield
… to identify and characterize pathogenicity genes of the bacterium. A rapid bioassay technique using soybean cotyledons was developed to evaluate the large number of mutants for their pathogenicity. One nonpathogenic mutant, NP1, did not multiply in soybean cotyledons. One …
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Elucidating the contributions of superoxide dismutases to staphylococcus aureus pathogenicity
Bacterial infections are a leading cause of death worldwide. One disease-causing organism is Staphylococcus aureus. Despite numerous methods used by the host immune system to combat infection, S. aureus is still a major health risk. Recently, the Centers for Disease Control and Prevention and the …
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Characterization of the type VI protein secretion system encoded in the Salmonella pathogenicity island 19 and its role in the pathogenicity of serotypes Gallinarum and Enteritidis
El genero Salmonella comprende a mas 2,500 serotipos conocidos distribuidos en dos especies: enterica y bongori. Estos serotipos difieren mucho en términos de patogenicidad y especificidad hospedero. Dos serotipos de Salmonella entérica son de especial relevancia: los serotipos Gallinarum y …
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Nutrient availability modulating physiology and pathogenicity of <i>Legionella pneumophila</i>
… <br></br><br></br>Expression of the important pathogenicity factor, the zinc metalloprotease, was regulated by iron availability. Common iron acquisition mechanisms, such as siderophores and transferrin receptors, were not elaborated by iron-limited cells. However, human transferrin was …
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Role of Silencing RNA fgsiR34 in Fusarium Graminearum's Pathogenicity to Wheat
… Inverse Repeat Transgene method and studied the pathogenicity of the mutant in wheat. Though no phenotypic alterations, such as spore production and growth rate on solid media, were found in the mutant in comparison with the wildtype strain, altered expressions of <em>Tri</em> genes and other …
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Infectivity and pathogenicity of toxoplasma gondii in vitro and in vivo
… were employed to get an insight into the pathogenicity and infectivity ofT. gondii. T. gondii, being an obligate intracellular parasite, can only be maintained in tissue culture or by passage through mice. Maintenance of parasite in laboratory animals may not be the method of choice due to …
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