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Showing 1 to 20 of 73 for “"Pathogenic Microbiology"”.
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Control of The Master Virulence Regulatory Gene Atxa In Bacillus Anthracis
<p>Transcription of the <em>Bacillus anthracis</em> structural genes for the anthrax toxin proteins and biosynthetic operon for capsule are positively regulated by AtxA, a transcription regulator with unique properties. Consistent with the role of <em>atxA</em> in virulence factor expression, a …
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Tetrodotoxin, fungal pathogen infection, and bacterial microbiome associations are variable in the skin microecosystems of two Taricha Newt species
<p>Chytridiomycosis is an amphibian disease linked to population declines and species extinctions, caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd). While chytridiomycosis can result in host death, some amphibians are less susceptible to severe infections through intrinsic factors …
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Impact of Chytrid fungus pathogen on the skin microbiome of frogs in northern Idaho and Turnbull National Wildlife Refuge, Washington
<p>Amphibians worldwide are under threat from the infectious disease chytridiomycosis, which is caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd). Bd is associated with the population declines of an estimated 501 species, 90 of which are presumed or confirmed extinct, making this the …
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Multiple virulence genes and other MRNA regulatory targets are differentially expressed in two Helicobacter pylori strains overexpressing small RNAs
… Strains possessing the cytotoxin-associated gene pathogenicity island (cagPAI) are especially likely to cause symptomatic disease and cancer through the action of the cagPAI Type IV secretion system and its associated cytotoxin, CagA. Although the genetic regulation necessary for these and other …
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High resolution modeling of tick density and detection of Rickettsia spp. in Dermacentor spp. ticks at Turnbull National Wildlife Refuge, WA
… were positive for Rickettsia peacockii, a non-pathogenic Rickettsia spp. that may also block the infection of R. rickettsii in ticks. While our results are inconclusive, they suggest that Rickettsia rickettsii is likely not present at TNWR.</p>
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Helicobacter pylori gene regulation by virulence region located sRNAs
… DNA region called the cytotoxin associated gene pathogenicity island (cagPAI) that encodes virulence factors. Gastrointestinal disease associated with H. pylori are more likely to occur in infections with cagPAI positive strains. Helicobacter pylori has few known transcriptional regulators, but …
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Molecular Detection of Tick-Borne Pathogens Associated With Ixodid Tick Species Infesting Migratory Songbirds and Ruminants
<p>Ticks are hematophagous arthropods and capable of inoculating various infectious agents to their vertebrate hosts. Ticks attached to birds and ruminants are capable of carrying tick-transmitted microorganisms. In our study, the prevalence of tick-borne pathogens was examined in ticks infesting …
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Evaluating efficacy of anti-Batrachochytrium dendrobatidis probiotic treatment on Pacific Chorus Frogs (Pseudacris regilla) at current and modeled climate change temperatures
<p>Amphibian populations are declining due to a variety of threats, including the chytrid fungal pathogen, Batrachochytrium dendrobatidis (Bd), the causative agent of the disease chytridiomycosis. Climate change and other stressors can have complicated interactions with amphibian disease. Some …
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Characterization of Helicobacter pylori sRNAs HPnc2525, HPnc2600, and HPnc2645
… a genomic region called the cytotoxin-associated pathogenicity island (cagPAI) are associated with an increased risk of severe disease. The cagPAI region encodes a type IV secretion system that transports the CagA effector into host gastric epithelial cells. Regulation of the cagPAI is a vital …
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The Effects Of The Estrus Cycle On Microbiota Composition And The Opportunistic Pathogen Listeria Monocytogenes Infection Process In Murine Models
<p>In the U.S., Listeria monocytogenes accounts for less than one percent of foodborne illnesses but has a 28% mortality rate. Infection in healthy individuals causes colonization of the intestinal lumen and subclinical noninvasive listeriosis. However, translocation of L. monocytogenes across the …
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The role of the skin microbiome in amphibian pathogen susceptibility in Turnbull National Wildlife Refuge
<p>The fungal pathogen, Batrachochytrium dendrobatidis (Bd), has led to the decline and extinction of many amphibian populations, but some bacteria in the skin microbiome can inhibit its growth. In Turnbull National Wildlife Refuge (TNWR) in eastern Washington, Bd is highly prevalent, but the role …
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The Thiol Specific Antioxidant (TSA1) Gene is Required for Survival in Macrophages and Oxidative Stress Resistance in Histoplasma Capsulatum
… capsulatum</em>(<em>Hc</em>) is a pathogenic fungus that causes one of the most common invasive fungal respiratory diseases, Histoplasmosis. <em>Histoplasma</em>undergoes a dimorphic shift from mold to yeast which is crucial to pathogenesis of the organism.</p> <p>The thiol specific …
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A study of Door Pulls on Isolation Carts in a General Hospital for Evidence of Contamination
… of Staphylococcus epidermidis. This is a nonpathogenic organism which probably came from the hands of whoever cleaned the cart.</p> <p>Of the forty-eight hour cultures, six were negative for any bacterial growth. Eight showed growths of Staphylococcus epidermidis and the remaining two showed …
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Analysis of the Clear Plaque Phenotype of the Bacteriophage HK75
The growth of bacteriophage HK75 is inhibited by specific mutations in the zinc binding domain of the host RNA polymerase beta prime subunit. It shares this rare property with bacteriophage HK022 and other phages that use RNA mediated antitermination to promote early gene expression. Recent genomic …
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The effects of salinity on the cutaneous microbiome and pathogen infection on the Pacific Tree frog (Pseudacris regilla) in Monterey Bay, California, USA
<p>Global climate change and infectious diseases are considered a leading cause of amphibian population declines worldwide. Changes in precipitation and salinity have altered watershed systems and microbial communities, reducing habitat availability and physiological performances for amphibian …
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Virulence of Drosophila C virus increased after a host shift and serial passage in Drosophila hosts
<p>The outcomes of novel host-pathogen interactions are unpredictable but can result in epidemics or pandemics. Exploring the initial encounter between a pathogen and a novel host species can elucidate why some pathogens successfully infect and adapt on a novel host when others fail. Much of our …
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Surveillance and monitoring of amphibian pathogens and evaluating the impacts of an associated Course-based Undergraduate Research Experience (CURE)
<p>Amphibians are a highly diverse class of vertebrates and crucial for natural ecosystems, inhabiting both aquatic and terrestrial environments at different life stages. However, amphibians are facing devastating declines largely due to the disease chytridiomycosis, caused by the fungal pathogens …
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Molecular Basis of Corynebacterium Diphtheriae Virulence and Infection In The Caenorhabditis Elegans Model Host
Corynebacterium diphtheriae is the causative agent of cutaneous and pharyngeal diphtheria in humans. While lethality is certainly caused by diphtheria toxin, corynebacterial colonization may primarily require proteinaceous fibers called pili, which mediate adherence to specific tissues. The type …
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