Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Partial-reprogramming"”.
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Rejuvenation of CNS Progenitors via Partial Reprogramming
Adult stem cells become less efficient at maintaining tissue integrity and repairing tissue damage with age. Oligodendrocyte progenitor cells (OPCs) are the largest population of stem cells in the adult CNS and give rise to oligodendrocytes. OPCs play a critical role in myelin regeneration …
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Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate
… accessible in Teff cells, thus undergoing partial reprogramming into a more functional state. Together, these findings suggest that continuous TOX expression in established Tex acts as a durable epigenetic barrier to reinforce the Tex developmental fate by simultaneously maintaining Tex …
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Fusion of bovine fibroblasts to mouse embryonic stem cells: a model to study nuclear reprogramming
… first part of this dissertation, we attempted reprogramming of three types of bovine somatic cells: fetal fibroblasts (bFFs), adult fibroblasts (bAFs), and bone marrow-derived mesenchymal stem cells (bMSCs), using six different culture conditions adapted from recent work in mice and humans. …