Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"Parkinson Disease"”.
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Tetrahydroisoquinoline Neurotoxins in Parkinson Disease
… (TIQ) derivatives in rodent, normal human and Parkinson disease (PD) brain, (2) quantify the levels of these TIQ derivatives in common food sources in an effort to link specific food intake patterns with the development of PD and (3) examine the neurotoxicity of select TIQ derivatives in human …
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A wearable health monitor to aid Parkinson disease treatment
Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2003.
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Cognitive and Behavioral Predictors of Fall Risk in Parkinson Disease
… a significant health issue for individuals with Parkinson disease (PD). Several factors have been identified that increase fall risk, including cognitive impairment, impulsiveness, and lower balance confidence, as well as PD-related characteristics. However, to date, no definitive predictor …
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Cognitive and Behavioral Predictors of Fall Risk in Parkinson Disease
… a significant health issue for individuals with Parkinson disease (PD). Several factors have been identified that increase fall risk, including cognitive impairment, impulsiveness, and lower balance confidence, as well as PD-related characteristics. However, to date, no definitive predictor …
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Biomechanical and Neural Factors Associated with Gait Dysfunction and Freezing in People with Parkinson Disease
<p>Parkinson disease: PD) is a progressive neurological disorder with no known cure, affecting one million Americans. Half of those with PD experience freezing of gait: FOG), manifested as an inability to complete effective stepping. Gait dysfunction and FOG are associated with falls, severe …
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Exploring a Role for the Parkinson Disease-Linked GBA1 Gene in Host Responses to Infections
Typical Parkinson’s Disease (PD) is a complex disease that arises from a combination of factors including genetics, environment, gene-environment interactions, sex and age. How these factors interact has yet to be elucidated. We have previously published roles for PD-linked genes in response to …
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Simultaneous Behavior Onset Detection and Task Classification for Patients with Parkinson Disease Using Subthalamic Nucleus Local Field Potentials
… for behavior onset detection of patients with Parkinson's disease (PD), as well as to investigate the models for classification of different behavioral tasks performed by PD patient. The detection is based on recorded Local Field Potentials (LFP) of the Subthalamic nucleus (STN), captured …
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Behaviour disorders dopamine-related
Today there is a growing awareness that in Parkinson's disease can occur motor and non motor disorders, in particular substances dependency syndromes and behavioral addiction. Objectives of the study. Objective of the study is to determine any changes frontal circuits potentially involved in the …
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In-home passive monitoring for medical applications
… it relates these health signals to symptoms of Parkinson Disease by deploying the sensor in a pilot study and comparing the health metrics to gold standard clinical assessments.
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The role of γ-polyglutamic acid in a circular economy: cost-effective production and wide-ranging applications of a bio-derived, biodegradable, and nonimmunogenic biomaterial
… alpha synuclein, was assessed in the context of Parkinson disease pathology (Chapter 6). Ultimately the inflammatory response of γ-PGA and γ-PGA-based composites (whey protein isolate- γ-PGA) were also evaluated (Chapter 7). This investigation found the ability of specific ions (Mn2+ and NaCl) to …
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Neuroninių sistemų slopinimo ir desinchronizavimo algoritmai /
… lead to epileptic seizures or symptoms of the Parkinson’s disease. Some patients of the Parkinson disease find an effective way to suppress involuntary movement of limbs by the electrical deep brain stimulation (DBS) – a procedure, when high-frequency electrical pulses are delivered to specific …
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Exercício aquático com dupla-tarefa para pacientes com doença de Parkinson avançada
… with dual-motor task on motor function of severe Parkinson Disease patients. Method: Twelve PD patients were divided into exercise (EG=7) and control (CG=5) groups. The EG completed 12 sessions of 30 min walking into deep water while executing dual-task, at moderate intensity, during 4 weeks with …
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Contribution à l’étude des peptides obliques impliqués dans des transconformations
… the α-synuclein sequence, a protein involved in Parkinson disease, has been synthetized and tested for lipid fusion. The fusogenic assays pointed out its destabilizing properties. These results support the hypothesis that tilted peptides could be involved in transconformational processes.
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Innovative analytical methods for Central Nervous System Drug analysis in biological fluids
… disorders, including psychosis, depression, Parkinson disease and epilepsy. Despite the great advancements obtained in the treatment of CNS diseases/disorders, partial response to therapy or treatment failure are frequent, at least in part due to poor compliance, but also genetic variability …
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Two Sides of The Same Coin in The Levodopa Treatment of Parkinson's Disease
Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder. PD is a characterized by selective loss of dopaminergic neurons in the pars compacta of the substantia nigra. Levodopa (L-dopa) and dopamine agonists have been most commonly used for symptomatic treatment. Since its …
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Alpha Synuclein Oligomers in Human Pathology: Significance of Nitrative Alpha Synuclein Modifications
… hallmark of synucleinopathies such as Parkinson disease (PD) and dementia with Lewy bodies (DLB), which are clinically characterized by motor and cognitive dysfunction. Recent evidence indicates that αSyn oligomer intermediates are the most neurotoxic species. However, the mechanism of …
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Synchronization in active networks
… behavior in neural networks, pattern formation, Parkinson disease, epilepsy, as well as behavioral activities. It has been reported that it mediates processes of information transmission and collective behavior in neural and active networks and communication processes in the Human brain. In this …
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Dementia Subtypes, Cognitive Decline and Survival Among Older Adults Attending a Memory Clinic in Cape Town, South Africa: A Retrospective Study
… Major Neurocognitive Disorder due to Alzheimer's disease (AD), 24(14.6%) Vascular Neurocognitive Disorder (VND), 6(3.6%) Dementia with Lewy Bodies (DLB), 5(3%) Parkinson disease-associated dementia (PDD), 3(1.8%) fronto-temporal dementia, 4(2.4%) mixed dementia and 6(3.6%) other types of dementia. …
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Visualization and manipulation of microRNA in neural cells
… sort out neural cells and transplant them in a Parkinson disease mouse model. Using this method I was able to reduce the frequency of tumor formation post transplantation. [1] It has been shown that miRNA-124 (miR-124) plays a crucial role in establishing and maintaining a neuronal transcription …
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