Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Parkinson's disease--Patients"”.
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Effect of Cigarette Smoking on Disease Progression in Idiopathic Parkinson's Disease Patients
… role against the development of idiopathic Parkinson’s disease (IPD). Despite this, there have been few studies focusing on whether cigarette smoking is able to slow IPD disease progression. The few that have examined this issue must be regarded with care due to their intrinsic …
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A study of motor control in healthy subjects and in Parkinson's disease patients
Parkinson's disease (PD) is a primarily motor disorder which affects at least half a million people in the US alone. Deep brain stimulation (DBS) is a neurosurgical intervention by which neural structures are stimulated electrically by an implanted pacemaker. It has become the treatment of choice …
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The Nature of the Processes, Representations, and Neural Substrates Which Support and Contribute to Motor Sequence Learning
The Parkinson's disease patients performed normally on both motor sequence learning tasks despite clear evidence of motor impairments demonstrable through independent clinical and neuropsychological testing. The results from the Parkinson's disease patients are the first to demonstrate normal motor …
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"Can I trust you with my medicines?" A grounded theory study of patients with Parkinson's disease perceptions of medicines management
Introduction: People with Parkinson's disease require individualised medication regimens to achieve symptomatic control whilst managing complications of the treatments and the underlying disease. Patients should continue to receive their individualised regimen when they are admitted to hospital but …
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3D spherical harmonic invariant features for sensitive and robust quantitative shape and function analysis in brain MRI
… changes in the thalami and brain ventricles of Parkinson's disease patients. This framework was then extended to generate functional features that characterize 3D spatial activation patterns within ROIs in functional magnetic resonance imaging (fMRI). To tackle the issue of intersubject …
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Anatomy of visual hallucinations and fluctuations of consciousness in Lewy body diseases
Lewy body diseases are characterized by parkinsonian disorders of movement and neuropsychiatric features of dementia, visual hallucinations and altered states of consciousness. The underlying neurobiological changes responsible for the psychiatric features are poorly understood. The integrative …
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Factors influencing the efficacy of delayed auditory feedback in treating dysarthria associated with Parkinson's disease
Parkinson's disease patients exhibit a high prevalence of speech deficits including excessive speech rate, reduced intelligibility, and disfluencies. The present study examined the effects of delayed auditory feedback (DAF) as a rate control intervention for dysarthric speakers with Parkinson's …
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Using visual feedback to guide movement: Properties of adaptation in changing environments and Parkinson's disease
… environment and how it is impacted by Parkinson's disease. Recent experiments in force learning have shown that adaptive strategies can be flexibly and readily modified according to the demands of the environment a person experiences. In Chapter 2, we investigated the properties of …
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Progress Towards Understanding Of Mechanisms Of Action Of Potent Multifunctional Disease Modifying Therapeutics For Parkinson's Disease & Investigating The Methamphetamine-Induced Striatal Microglia Activation.
… MECHANISMS OF ACTION OF POTENT MULTIFUNCTIONAL DISEASE MODIFYING </p> <p>THERAPEUTICS FOR PARKINSON'S DISEASE.</p> <p>by</p> <p>MRUDANG MANOJKUMAR SHAH</p> <p>December 2013</p> <p>Advisor: Dr. Aloke Dutta</p> <p>Major: Pharmaceutical Sciences</p> <p>Degree: Doctor of Philosophy</p> <p>Our long …
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Individuals with Parkinson's disease and their experiences with changes in communication and behavioral speech therapies
Background: Parkinson's disease (PD) is a major public health concern that affects the lives of nearly one million older adults in the United States. According to the World Health Organization, disability and deaths related to PD are rising more than any other neurological disease (2022). PD is …
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A phenomenological study of partners of people with Parkinson's disease who demonstrate communication changes
Parkinson's disease is a common progressive neurological illness for which there is no known cure. While the cardinal signs are tremor, bradykinesia or slowness of movement, muscle rigidity and postural instability (Jahanshahi & Marsden, 1998, p.3) the patient may face an extended number of years …