Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Paraventricular Nucleus of the Hypothalamus"”.
-
The Role of the Circadian Clock in the Paraventricular Nucleus of the Hypothalamus in Diurnal Energy Balance
… in physiology and metabolism. Maintained at the level of individual cells throughout the body, the circadian clock is necessary for driving tissue-specific temporal programs of energy balance. Though loss of the circadian transcription factor, BMAL1, in the paraventricular nucleus (PVN) of …
-
Neurons projecting to the paraventricular nucleus of the hypothalamus are activated and contribute to cardiorespiratory responses to systemic acute hypoxia
Activation of peripheral and central chemoreceptors contributes to homeostatic responses that maintain optimal blood gas levels, including oxygen and carbon dioxide. Brainstem neurons in the nTS and CVLM integrate and modulate chemosensory information and participate in control of cardiorespiratory …
-
Neuromedin U Acts via the Paraventricular Nucleus of the Hypothalamus and the Dorsal Raphe Nucleus to Regulate Motivation for High-Fat Food
… intake in obese individuals. A novel regulator of motivation for food may be neuromedin U (NMU), a highly-conserved neuropeptide that influences food intake. Although these effects of NMU have primarily been attributed to signaling in the paraventricular nucleus of the hypothalamus (PVN), NMU …
-
Integration of Homeostatic and Hedonic Brain Centers in the Regulation of Feeding Behaviors
… behaviors, namely pathological overconsumption of high-fat food. Pathological overconsumption of high-fat food is potentiated by aberrant homeostatic feeding behavior (i.e. titration of caloric intake), which typically associates with hypothalamic brain nuclei, specifically the paraventricular …
-
The External Globus Pallidus: Bidirectional Control Over Anxiety-Related Behavior Mediated By Crfr1
<h1>Abstract</h1> <p>THE EXTERNAL GLOBUS PALLIDUS: BIDIRECTIONAL CONTROL OVER ANXIETY-RELATED BEHAVIOR MEDIATED BY CRFR1</p> <p>Albert Lee Joseph Hunt, Jr., B.S.</p> <p>Advisory Professor: Shane Cunha, Ph.D.</p> <p>Corticotropin-releasing factor receptor 1 (CRFR1), the principle receptor …
-
Naturally occurring variations in defensive burying behavior are associated with differences in central neuropeptide expression in the male rat
The shock prod defensive burying test has proven incredibly reliable and instrumental in determining the underpinnings of normal anxiety in rodents. Largely ignored in tests of defensive burying, however, is the capacity for individual animals to display marked variations in active and passive …
-
Hypothalamic mechanisms of appetite regulation involve stress response and epigenetic modification
Appetite regulation is primarily mediated by the hypothalamus, within which many neurotransmitters that regulate feeding are shared by the stress response circuitry. Stressors, especially those occur during critical periods of life, influence epigenetic programming and gene expression in the …
-
Molecular and cellular mechanisms of energy homeostasis in birds
Hypothalamus and adipose tissue are essential central and peripheral sites regulating energy homeostasis. Disruption of energy homeostasis can lead to diseases like anorexia and obesity in humans and reduced productivity in animals. Therefore, integrating knowledge in hypothalamic appetite …
-
Ossitocina nella Sostanza Nera del ratto: azione sull'attività locomotoria e interazione con i neuroni dopaminergici, glutammatergici e GABAergici nigrali
Oxytocin, the neurohypophyseal hormone well-known for its hormonal role in lactation and parturition, also exerts a wide range of effects acting in the Central Nervous System as a neuromodulator or neurotransmitter. An increasing number of experimental studies have suggested that, in rodents, …
-
Modelling altered Glucocorticoid Sensitivity: From HPA axis to metabolic abnormalities in mice and humans
The primary determinants of tissue glucocorticoid action are glucocorticoid receptor (GR) density and intracellular levels of ligand, the latter determined both by activity of the hypothalamic-pituitary-adrenal (HPA) axis and cellular activity of 11beta- hydroxysteroid dehydrogenase (11beta-HSD) …
-
Neurodevelopmental and Behavioral Consequences of Serotonin System Disruption via Early Life Exposure to SSRI Antidepressants
… women suffering with depression, although the long-term impact of these medications on exposed offspring are poorly understood. Perinatal SSRI exposure alters human offspring's neurodevelopment and increases risk for psychiatric illness in later life. Rodent studies suggest that perinatal …
-
Neurochemical and functional characterisation of the Melanin-concentrating hormone system in the rat brain
The central melanin-concentrating hormone (MCH) system has been intensively studied for its involvement in the regulation of feeding behaviour and body weight regulation. The importance of the neuropeptide MCH in the control of energy balance has been underlined by MCH knock out and …