Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Parasitic worms."”.
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The assessment of the contamination of soil-transmitted helminth life stages in the environment and under fingernails
… helminths (STHs) are a group of intestinal parasitic worms that are transmitted through contact with infectious stages in the environment (often soil, which refers to their common name). The STH species that predominantly infect humans are Ascaris lumbricoides Trichuris trichiura and the …
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The Seasonality and Parasite Richness and Prevalence of the Weddelli’s Saddleback Tamarin (Leontocebus Weddelli)
<p>This study surveyed the intestinal helminths (parasitic worms) of Weddelli’s saddleback tamarins (<em>Leontocebus weddelli</em>), focusing on seasonality in parasite prevalence and richness. The collaborative study with Field Projects International took place at the Estación Biológica Rio Los …
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Modulation of macrophage metabolism and function by the helminth peptide FhHDM-1
Parasitic worms have evolved sophisticated strategies to regulate their host’s immune response, to prevent expulsion and establish chronic infections. Understanding how they achieve this offers a therapeutic strategy for the treatment of human diseases which are caused by unregulated inflammation. …
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Development and application of genomic tools for characterising genetic variation in soil-transmitted helminths
Soil-transmitted helminths (STHs) are intestinal parasitic worms that represent a significant global health challenge, perpetuating poverty and disease. For decades, the diagnosis of STHs has depended on the microscopic detection and identification of eggs or larvae in faecal samples. However, …
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The immunomodulatory properties of helminth-derived products on dendritic cell maturation and function
Parasitic worms and molecules derived from them drive Th2/Treg immune responses in mammalian hosts and have powerful anti-inflammatory properties which are shown to have therapeutic effects on inflammatory diseases. Using products derived from the helminth parasites Fasciola hepatica and Ascaris …
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The Search for Novel Anthelmintic Targets: Characterizing Alternative Metabolic Pathways in Caenorhabditis elegans
… a quarter of the human population is infected by parasitic helminths which also infect and place a large economic burden on the agricultural industry. Unfortunately anthelmintic resistance is a growing problem. Helminths survive long periods of low to no oxygen in their hosts, but their anaerobic …
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An AI-Based Machine Vision Model for the Diagnosis of Neglected Tropical Diseases
… on Schistosoma mansoni. NTD infections caused by parasitic worms are collectively known as helminthiases, the most important of which are soil-transmitted helminthiasis and schistosomiasis, both potentially fatal parasitic infections. Schistosomiasis, which includes intestinal schistosomiasis …
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Bystander influence of nematode exposure on subsequent herpesvirus infections in vivo
Parasitic worms have the ability to modulate the hosts immune response to promote host control of the infection and also parasite survival in the host. Helminth infections classically induce a potent Th2-biased and regulatory immune imprint. This immune response also influences unrelated …
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POPULATION GENETIC APPROACHES FOR THE STUDY OF COMPLEX TRAITS: FOCUS ON INFECTIOUS AND AUTOIMMUNE DISEASES
… these latter genes have evolved in response to parasitic worms, but a subset of disease alleles for inflammatory bowel disease and celiac disease have increased in frequency in response to non-helminthic pathogens (i.e. viruses and bacteria). At the genome-wide level, the identification of …
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Characterisation of an immune-modulating peptide secreted by a helminth worm
Parasitic worms (helminths) have evolved mechanisms to potently modulate the mammalian immune response to ensure their long-term survival, while concomitantly preventing excessive tissue pathology within the host. The outcome of this activity is a potent suppression of mammalian pro-inflammatory …
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Exploring the Role of Wolbachia Endobacteria in the Biology of Filarial Nematode Parasites
Filarial nematodes are vector borne parasitic worms that cause a variety of disfiguring and disabling diseases, including lymphatic filariasis and onchocerciasis. Many filarial species require <italic>Wolbachia</italic> endobacteria: family: Rickettsiaceae) to carry out their life cycle. Studies …
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The feeding apparattus [sic] of the nematode parasite Globodera pallida
… simple animals known commonly as roundworms or thread worms. They are cylindrical non-segmented cigar shaped organisms distinguishing them from other types of worm. However, despite this simplicity these helminths are the most ubiquitous animals on earth and have successfully managed to …