Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Parasite lifecycle"”.
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Exploration of the malaria parasite lifecycle stages and strains circulating in natural infections at single-cell resolution
… half million. Extensive diversity in malaria parasites is a key challenge in developing effective interventions. Many infections constitute several strains, and this complicates malaria studies since it is hard to disentangle strains using traditional bulk approaches. There are also parasites …
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Chemical Genetic Approaches for Elucidating Protease Function and Drug-Target Potential in Plasmodium Falciparum
Plasmodium falciparum is a protozoan parasite and the causative agent of malaria, which kills upwards of 1 million people annually. With the increasing prevalence of drug-resistant parasites, considerable interest now exists in the identification of new biological targets for the development of new …
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Investigating the structure-function relationships of Plasmodium Haem Detoxification Protein and Phosphatidylinositol 4-kinase
The human malaria parasite Plasmodium falciparum relies on proteins and protein-mediated processes to survive, replicate in the host and evade the host's immune response. This study focuses on two Plasmodium proteins: (i) Haem Detoxification Protein (HDP) which has been reported to catalyse …
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Norway lobster and Hematodinium sp. in the Clyde, modelling the population dynamics of a commercially important host-parasite system
… dinoflagellate species (Hematodinium sp.).This parasite causes drastic changes in the organs, tissues and haemolymph of infected individuals and is ultimately fatal. The overall meat quality of infected animals is also significantly reduced which leads to a drop in commercial value. …
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Investigation of Trans-factors responsible for the developmentally linked instability of a highly regulated mRNA in Trypanosoma brucei
*Trypanosoma brucei*, a protozoan pathogen of both humans and livestock, has a number of divergent features arising from its history as an early branching eukaryote. One such feature is an RNA polymerase II gene expression system in which genes of diverse functions and expression profiles are …