Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 19 of 19 for “"Parasite Burden"”.
-
Immune gene expression and diversity in relation to gastrointestinal parasite burden in small mammals
… in response to the reoccurring adaptations of parasites and pathogens. A large number of MHC studies were performed in a wide range of wildlife species aiming to understand the role of immune gene diversity in parasite resistance under natural selection conditions. Methodically, most of this …
-
Parasite Burden and Potential Virus Exposure in the Gopher Tortoise <em>(Gopherus polyphemus)</em>
… and such a role may be related to endo- and ectoparasite loads in the tortoise. To assess this hypothesis, a survey of gopher tortoises from areas in southeastern Georgia where EEEV is present was conducted from May 2001 to August 2002. In this survey, tortoise blood samples were tested for the …
-
Linking environmental variation across the Scottish Highlands with red deer (Cervus elaphus) trace element status, parasite burden, and skeletal morphometry
… extensively quantified geographic variation in parasite prevalence or nutritional essential and non-essential trace/macro and toxic element status. Given the well-recognised effects of sub-lethal parasitism and sub-optimal nutrition on performance of ruminants (from an agricultural perspective; …
-
Coping with Chronic Infection: The Role of Glucocorticoid Hormones in Mediating Resistance and Tolerance to Parasites
… to individual differences in the use of two parasite defense strategies, resistance and tolerance. Resistance entails reducing parasite burden by removing parasites or restricting parasite reproduction. Tolerance involves minimizing the costs associated with a given parasite burden. Genetic …
-
Does variability matter? Major histocompatibility complex (MHC) variation and its associations to parasitism in natural small mammal populations
… which have a key role in immune defence, and parasite burden in different small mammal species. I assessed the importance of MHC variation for parasite burden in small mammal populations in their natural environment. To understand the processes shaping different patterns of MHC variation I …
-
The role of vector-derived microbiota and co-localization in the dissemination of vector transmitted pathogens
… strategies due to the ability of Leishmania spp. parasites to disseminate from the initial site of infection in the skin to the internal organs following transmission by the bite of an infected sand fly vector. This study investigated the role of inoculation method and the vector, sand fly …
-
Caracterização da resposta imunometabólica frente a infecção por Leishmania amazonensis e Leishmania braziliensis em macrófagos de camundongos BALB/C
… a serious public health problem. These parasites infect cells of the innate immune system, particularly macrophages, and possess the ability to modulate cellular metabolism during infection, favoring their survival. The present study investigates the metabolic alterations induced by …
-
Investigation the immunological response elicited to the gastrointestinal nematode pinworm (Syphacia obvelata)
… animals. The direct transmission of the parasite by contaminated food, water and bedding result in their continual re-exposure to the host, making the control of pinworm in animal holdings quite difficult. Syphacia obvelata, mouse pinworm, has been shown to interfere with research goals …
-
Characterization of interleukin-4 induced gene-1 (IL-4I1) as a host immunoregulator to cutaneous leishmaniasis in cell based models
… of nitric oxide for killing of intracellular parasites. Contrastingly, M2 macrophages allow for parasite survival through stimulation of cytokines such as IL-4 and IL-13 and release of urea that supports parasite growth. Candidate genes responsible for promoting M1 or M2 macrophages are being …
-
The prevalence and impact of internal parasites on the wild rabbit, Oryctolagus cuniculus (L.)
… the presence of cestode, protozoan and nematode parasites. Parasites were identified and their burdens estimated.<br/>The nematode parasites found were Graphidium strigoswn, Trichostrongylus retortaeformis and Passalurus ambiguus. The overall prevalence of G. strigosum was 92%, with a mean …
-
Endoparasites of working donkeys in Ethiopia: epidemiological study and mathematical modelling
… donkeys and horse in their reaction to the parasite and/or between cyathostomins of donkeys and horses. The results of the stimulation of the effect of various protocols for the timing and frequency of anthelmintic treatment on the adult cyathostomin worm burden have shown that treating …
-
Pathological and physiological relationships of parasitic disease in a select cottontail rabbit population
… factorial experiment to determine the effects of parasite reduction on host physiology. Rabbits were treated with insecticide-generating collars (Sergeant's Sentry Dog Collar) and a broad spectrum antihelminth drug (Tramisol, American Cyanamid) to reduce parasite burdens. Rabbits were confined in …
-
Congenital Chagas Murine Model Development and Nanovaccine Efficacy Against Maternal-fetal Trypanosoma cruzi Pathogenesis
Maternal infection with Trypanosoma cruzi (Tc) parasite can lead to the vertical transmission from mother to fetus known as congenital Chagas’ disease (cCD). The objective was to develop a murine model of cCD to test the efficacy of a DNA nanovaccine developed by our laboratory. In this …
-
CD4+ T cells in the pathogenesis of visceral leishmaniasis
… and bone marrow. Patients present with high parasite burdens in visceral organs, splenomegaly, cachexia, pancytopenia and will progress to death if not treated. Control of Leishmania infection is dependent on Th1 (IFNγ producing) CD4+ T cells, which activate macrophages to produce nitric …
-
Identification of Host and Parasite Factors Mediating the Pathogenesis of Severe and Cerebral Malaria
… malaria infection results in diverse host and parasite responses that impact disease outcome. The aim of this study was to identify differential host and parasite responses in a murine model of severe malaria, Plasmodium berghei ANKA (PbA), in CM-susceptible and CM-resistant mice; and to …
-
Evasion of interferon-gamma responses by Toxoplasma gondii in murine and human fibroblasts
… pathogens with their hosts. The intracellular parasite Toxoplasma gondii is an excellent model organism for co-evolution studies because its hosts include all warm-blooded animals, and genetically diverse Toxoplasma strains may be adapted to specific hosts. Toxoplasma must evade host immunity …
-
Health Surveillance of Thinhorn Sheep (Ovis dalli) Herds in British Columbia and Alaska
… health measures including nutritional status, parasite burden, contaminant exposure, stress, pregnancy, and indices of body condition. From 2017 to 2020 we collected tissue and blood samples from 46 Stone’s sheep ewes and immature rams live-captured in the Skeena and Peace regions of British …
-
Studies on development of a Leishmanial vaccine
… by infection with the obligate intracellular parasite of the genus Leishmania. Leishmaniasis is a public health problem; it is estimated that approximately 12-15 million people worldwide are infected. An estimated 1.5-2 million new cases occur each year, 350 million people are at risk of …
-
Understanding the molecular mechanisms controlling gametogenesis and virulence in Cryptosporidium parvum
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms