Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 43 for “"Paraplegia"”.
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Compression paraplegia
… is pressure upon the cord, whether a true motor paraplegia in the narrower sense of the word, that is paralysis of the lower limbs, is present or not.
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Nonlinear robust control of functional electrical stimulation system for paraplegia
… (FES) for sit-to-stand movement restoration in paraplegia subjects. The scarcity of FES assistive devices was due to the inability of the developed equipment to attain clinical acceptance. Applications of control systems have shown fruitful results. And based on the literature, further …
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Spiritual Well-Being and Quality of Life among Persons with Paraplegia
… gender, ethnicity, and QOL while living with paraplegia one year and longer. A descriptive, correlational, cross-sectional design, with convenience sampling of 75 participants was implemented. Instruments used to measure the influence of variables included Ellison's Spiritual Well-Being Scale, …
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Characterisation of cardiorespiratory responses to electrically stimulated cycle training in paraplegia
… week) in 9 male and 2 female individuals with paraplegia. Outcomes were investigated using a novel, sensitive test bed that accounted for both internal and external power production (Pt). The test protocol permitted high resolution analyses of cycling power and metabolic thresholds, and a …
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Visualizing Roles of Spastic Paraplegia Proteins in Organizing Axonal ER in Live Drosophila
… axon degenerative disease, hereditary spastic paraplegia (HSP). However, the extent and mechanisms by which HSP proteins contribute to axonal ER organization and dynamics are unclear. To understand these mechanisms, there is a need to visualize axonal ER in wild-type and mutant live axons. I …
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Investigating the function of the hereditary spastic paraplegia protein spastin in the endomembrane system
Hereditary spastic paraplegias (HSPs) are genetically inherited neurological diseases characterised by the distal axonal degeneration of corticospinal neurons. Of the 80 genes currently associated with HSP, mutations in SPAST, encoding the protein spastin, are by far the most common cause of …
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Testing roles of Hereditary Spastic Paraplegia genes in axonal endoplasmic reticulum modelling in Drosophila
Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by progressive lower limb spasticity due to axonal degeneration. Smooth endoplasmic reticulum (ER) forms a longitudinal network within the axon; common mutations in HSP affect proteins of the spastin, atlastin, REEP …
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Balance and gait problems in people with hereditary spastic paraplegia: patient experience, underlying mechanisms, and clinical management
Contains fulltext : 225372.pdf (Publisher’s version ) (Open Access)
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Testing roles of Hereditary Spastic Paraplegia (HSP) proteins in organization of axonal endoplasmic reticulum (ER) and ER-mitochondria contacts
The Hereditary Spastic Paraplegias (HSPs) are a group of genetically heterogeneous, neurodegenerative and neurodevelopmental diseases characterised by spasticity and lower limb weaknesses. Some known causative genes imply the importance of endoplasmic reticulum (ER) function and morphogenesis in …
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“Half a man?” Still a human: Narratives on the impact of a spinal cord injury on coloured men living with paraplegia
… of a spinal cord injury on men living with paraplegia, while existing research in South Africa and the Global South lacks knowledge on these narratives. This study explored the narratives on the impact of a spinal cord injury on fifteen coloured men living with paraplegia on the Cape Flats. …
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Functional electrical stimulation (FES) leg cycling exercise in paraplegia: a pilot study for the definition and assessment of exercise testing protocols and efficacy of exercise
A custom FES-cycling ergometer equipped with an electric motor and an integrated feedback system for accurate control of exercise workrate and cadence has been employed in this study. This experimental setup allowed the imposition of arbitrary workrate profiles with high precision and provided the …
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The Relationship Between Lean Body Mass, Resting Metabolic Rate, and Peak Oxygen Consumption in Spinal Cord-Injured and Able-Bodied Individuals
… of 50 participants (10 male individuals with paraplegia, 9 female individuals with paraplegia, 6 male individuals with quadriplegia, 16 male able bodied and 9 female able bodied). RMR was assessed using open circuit spirometry. The amounts of LBM, MFL, and BMC were assessed using dual energy …
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An investigation of position and force during gait-mimicking finger motions
… person without the ability to use their legs (paraplegia) and sometimes, without the ability to use their arms and legs (tetraplegia or quadriplegia). Currently, primitive forms of feed-forward functional electrical stimulation (FES) and special orthotics are available for persons with …
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Spinal compression in childhood : the University of Cape Town experience
… dysraphism and non-compressive causes of paraplegia, such as Guillain-Barre Syndrome and poliomyelitis.
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A novel approach to user controlled ambulation of lower extremity exoskeletons using admittance control paradigm
… ambulatory problems confronting individuals with paraplegia. Paraplegia due to spinal cord injury (SCI) can cause motor deficit to the lower extremities leading to inability to walk. Though wheelchairs provide mobility to the user, they do not provide support to all activities of everyday living …
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Effects of physical activity levels and nutritional intake on skeletal muscle protein turnover and cellular signaling
… mTOR activity may play an important role in paraplegia-induced muscle atrophy as 10 weeks of paraplegia in rats significantly downregulated the mTOR pathway. In humans and compared to modest carbohydrate ingestion, higher amounts of carbohydrate and consequent increases in circulating insulin …
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Hand control of bipedal balance in quiet standing: implementations for lower extremity exoskeleton
… One of the main balance related disorders is paraplegia due to spinal cord injury. People with a complete spinal cord injury have motor and sensory impairment that greatly reduces the ability to move their lower extremities. In recent years, lower extremity exoskeletons that apply torques …
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Spinal cord injury and quality of life: what determines quality of life and what is the relationship between physical activity, fitness and quality of life
… (high quadriplegia, low quadriplegia and paraplegia). Results showed that physical activity was significantly correlated with the total score for objective quality of life in the groups of persons with high quadriplegia and paraplegia. Qualitative results supported these findings …
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Influence of rear wheel tire type on wheelchair propulsion biomechanics
… propulsion mechanics. Four persons with paraplegia and four persons with tetraplegia propelled their own wheelchairs on a roller system at self-selected speed using five different pairs of tires. Upper limb and trunk kinematics, perceived exertion, stroke pattern and the temporal …
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Transgenic complementation of rumpshaker with wild type proteolipid protein
… Pelizaeus Merzbacher disease (PMD) and Spastic paraplegia type 2(SPG2) in man (Hudson et al., 2004). A single base change mutation in our spontaneous mouse model rumpshaker (Plpjp-rsh)(Ile186Thr) (Schneider et al., 1992) generates a misfolded protein resulting in dysmyelination and increased …
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