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Showing 1 to 6 of 6 for “"Parallel screening"”.
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Characterization and systems integration of microreactors
… capabilities, point-of-use synthesis, and highly parallel screening methods. However, the use of integrated circuit-like reaction devices, such as the MIT thin-film microreactor, also gives rise to a spectrum of new engineering challenges with respect to reactor system integration and scale-up …
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Rapid screening of PEM FC cathode catalysts
… of fast high-throughput testing methods. Fast screening techniques enable a large number of catalysts to be tested in a relatively short time under the same conditions.<br/><br/>This project was focused on developing systems for screening catalysts used for the oxygen reduction reaction (ORR) …
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High throughput RNA interference based screen for the identification of genes implicated in listeria monocytogenes infection
… of infection. Here we describe a high throughput screening approach to assay for potential human host factors involved in L. monocytogenes infection. In this methodology, we applied a high-density siRNA array comprising of the kinome, phosphatome, ubiquitome and protease encoding human genes that …
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Mixing in high throughput experimentation reactors
… and pharmaceutical industries enable the parallel screening of potential formulations. Such tasks only require a fraction of the raw material and experimental time that are needed in conventional lab scale reactors. However their small sizes (~ 15-250 ml) contribute to a low Reynolds …
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On-chip parallel detection of foodborne pathogens using loop-mediated isothermal amplification
… in silicon oxide wells, enabling multiplexed screening of virulence genes of Listeria monocytogenes, Escherichia coli, and Salmonella. Droplets of 30 nL with reagents for nucleic acid amplification and lysate of suspected pathogens are arrayed on micro-machined wells with an automated …
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Design and synthesis of novel non peptidomimtic beta-secretase inhibitors in the treatment of Alzheimer's disease
… groups. The inhibitors should be tested on a parallel screening in order to have a more reliable data prior to be tested into cellular assay. With this aim, preliminary cellular BACE1 inhibition assay carried out on lipocrine confirmed a good cellular activity profile (EC50 = 3.7 mM) …