Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Paracoccus denitrificans"”.
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The Impact of Nitrite on Aerobic Growth of Paracoccus denitrificans PD1222
The effect of nitrite stress induced in Paracoccus denitrificans PD1222 was examined using additions of sodium nitrite to an aerobic bacterial culture. Nitrite generates a strong stress response in P. denitrificans, causing growth inhibition. This is dependent on both the concentration of nitrite …
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Structure-function studies of respiratory complex I from Paracoccus denitrificans using membrane mimetics
… elusive. Complex I from the α-proteobacterium Paracoccus denitrificans is the closest bacterial relative of the mammalian enzyme and provides a minimal, genetically tractable system for studying its mechanism. However, the structure of the enzyme remains unknown, due to its intrinsically …
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Paracoccus denitrificans as a model system for studying the mechanism of respiratory complex I
… elusive. In this thesis, the α- proteobacterium Paracoccus denitrificans is developed and presented as a powerful model system for understanding mitochondrial complex I, combining interrogative biophysical and structural characterisation with the potential for mutagenesis in every subunit. First, …
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Biochemical Studies on the Catalytic Cycle of Cytochrome C Oxidase in Rhodobacter Sphaeroides
… crystal structure of cytochrome c oxidase from Paracoccus denitrificans reveals two proton channels leading to the binuclear center. (Iwata, S., Ostermeier, C., Ludwig, B., & Michel, H. (1995) Nature 376, 660--669) One channel is referred to as the K-channel after the highly conserved lysine-362 …
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The regulation of denitrification in P. denitrificans
… gene expression data in continuous cultures of Paracoccus denitrificans revealed a majority of highly expressed genes were co-regulated by CPR/FNR type transcriptional regulators. Motif analysis of the upstream region showed similar patterns recognizable by FNR. P. denitrificans expresses three …
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Structural characterization of the two copper proteins nitrous oxide reductase from Pseudomonas stutzeri and laccase Lcc5 from Coprinopsis cinerea
… Untersuchungen an diesem Protein aus Paracoccus denitrificans, Marinobacter hydrocarbonoclasticus und Achromobacter cycloclastes ermöglichten Einblicke in dessen Struktur: Das Protein formt ein "Head-to-Tail"-Dimer, dessen Bildung notwendig für die enzymatische Reaktion ist. Jedes …
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Mutagenesis investigations into proton transfer pathways and control points in respiratory complex I
… the genetically tractable α-proteobacterium Paracoccus denitrificans and its accompanying toolkit of biochemical, biophysical and structural techniques was used to investigate proton translocation in the membrane domain, using amino acid substitutions to target, disrupt and identify proton …
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Investigating the rate-limiting step of mitochondrial complex I catalysis
… in the central axis were investigated using the *Paracoccus denitrificans* model system. Mutants of residues involved in the energy propagation pathway and subunit hydration channel gating were evaluated using solvent isotope effect and proton pumping experiments. These mutations all exhibited a …
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Chlorid, ein neues Signalmolekül für Bakterien
… Corynebacterium glutamicum, Escherichia coli, Paracoccus denitrificans, Proteus mirabilis, Proteus vulgaris, Staphylococcus aureus, Thermus thermophilus und Vibrio fischeri.
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Advancing biocatalytic technologies for degradation of micropollutants in drinking water
… waste brine. Nitrate biocatalysts from Paracoccus denitrificans and Haloferax denitrificans reduced nitrate. Tracking dinitrogen formation using stable isotopes in the 12% sodium chloride solution, the combined P. denitrificans and H. denitrificans biocatalysts reduced nitrate into a …
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Electron cryomicroscopy structures of respiratory supercomplexes from alphaproteobacteria suggest mechanisms to enhance catalysis and to prevent deactivation of respiratory complex I
… supercomplex assemblies are presented from Paracoccus denitrificans, a close relative of the mitochondrial progenitor. The initial part of the thesis describes the procedure to purify the respiratory supercomplexes from P. denitrificans membranes, the biochemical and mass-spectrometric …