Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Pangenomes"”.
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Modeling Sequence Uncertainty in Comparative Genomics with a Probabilistic DNA Representation
… to pervasive reference biases in genomics. Graph pangenomes have recently emerged to address these limitations by representing genetic variation across populations as bidirected graphs. While promising, these approaches are still developing and are not yet fully integrated with widely used …
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A tale of two clades: genome evolution of oomycetes and fungi.
… other criteria. The fourth study looks at the pangenomes of four model fungal species, and compares the evolution of genomic variation, virulence and environmental adaptation within each species. The final study presents a refined iteration of the methodology used in the previous pangenome …
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Graphical pangenomics
… from large vertebrate genomes to microbial pangenomes. To demonstrate the utility of this approach, I use my implementation to solve resequencing and alignment problems in the context of Homo sapiens and Saccharomyces cerevisiae. I use graph visualization techniques to explore variation …
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New insights into Transposable Elements from high quality genome sequences across diverse animals
… to obtain transposable element libraries from pangenomes of different haplotypes. I show how Pantera compares to similar tools and I present results of its application to a diverse range of species. These include 404 species of Lepidoptera from the Darwin Tree of Life where we found new …
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Genome evolutionary studies of the Salmonella enterica serovars: implications for the dynamics of horizontal gene transfer, the pangenome concept, and bacterial and archaeal taxonomy
… pangenome. We also demonstrate that supraspecies pangenomes are widespread across the microbial world; they are found amongst other bacterial lineages and even archaeal lineages. Further, since these genes pools are shared beyond the species level implies that this phenomenon has significant …