Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Palliative treatment"”.
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Comparison of double-layered(ComVi) stents with polyurethane covered stents in palliative treatment of unresectable malignant gastroduodenal obstruction
배경: 자가팽창형 금속스텐트는 악성 위십이지장 폐쇄의 고식적 치료에 현재까지 널리 사용되고 있다. 자가팽창형 금속스텐트에는 피막형과 비피막형의 두 가지 종류가 있는데, 비피막형 스텐트의 경우 종양의 내증식으로 인한 폐쇄가 빈번하다는 단점이 있으며, 피막형 스텐트의 경우 스텐트의 일탈이 문제가 되었다. 따라서 이 문제를 해결하기 위해 새로운 이중막 스텐트(ComVi)가 개발되었으며, 이는 피막형 스텐트 표면에 금속망을 더하여 종양의 내증식과 스텐트의 일탈을 동시에 줄일 수 있도록 고안되었다. 본 연구는 악성 위십이지장 폐쇄 환자에서 …
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A Coupled CFD-Lumped Parameter Model of the Human Circulation: Elucidating the Hemodynamics of the Hybrid Norwood Palliative Treatment and Effects of the Reverse Blalock-Taussic Shunt Placement and Diameter
The Hybrid Norwood (HN) is a relatively new first stage procedure for neonates with Hypoplastic Left Heart Syndrome (HLHS), in which a sustainable univentricular circulation is established in a less invasive manner than with the standard procedure. A computational multiscale model of such HLHS …
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A prospective randomised trial comparing plastic and uncovered self-expanding metal stents for palliation of symptomatic jaundice in patients with malignant distal biliary obstruction
… uncovered self-expanding metal stents (SEMS) for palliative treatment of patients with inoperable malignant distal biliary obstruction in a public hospital in South Africa. Methods: From January 2009 to December 2013, 40 patients who were admitted to a tertiary academic centre because of distal …
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A prospective, longitudinal, observational study to assess the health-related quality of life of patients with pancreatic ductal adenocarcinoma in the South African context
… diagnostic procedures and surgical and oncologic treatment, the overall prognosis remains dismal. GLOBOCAN 2020 ranks PDAC as the 7 th leading cause of all cancer deaths. There are no reliable statistics on the incidence of PDAC in South Africa. The National Cancer Registry South Africa of 2017 …
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In-Vitro and In-Silico Investigations of Alternative Surgical Techniques for Single Ventricular Disease
… three-staged surgical approach serving as a palliative treatment for this anomaly, entails multiple complications and achieves a survival rate of 50%. Hence, to reduce the morbidity and mortality rate associated with the second and third stages of the existing palliative procedure, the novel …
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Corneal epithelial debridement for the treatment of painful bullous keratopathy: A pilot study
… manual epithelial debridement (MED) for the treatment of painful bullous keratopathy (BK). Methods: In a prospective interventional case series, 15 eyes of 15 consecutive patients presenting with painful BK of varying aetiology underwent MED. Patients were followed up at 10 days, 1 month, 2 …
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Mild and Convenient Methods to Prepare N-Alkyl Tacrines
… inhibitors (AChEI) are the mainstay for the treatment of AD. Acetylcholinesterase (AChE) catalyzes the hydrolysis of acylcholinesters with a relative specificity for acetylcholine (ACh). Observation of a deficiency of cholinergic neurotransmission in AD led to the development of AChEI as the …
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Efficacy of novel immunotherapeutic strategies targeting L1CAM in pancreatic cancer
… primary tumor resection as putative curative treatment, early metastasis and profound therapy resistance. A promising target for new therapeutic options is the L1 cell adhesion molecule (L1CAM) which is upregulated in PDAC cells in most PDAC tissues and associated with different hallmarks of …
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Specialist palliative day care : patients' perspectives
… Psychosocial Experiences of Attending Specialist Palliative Day Care: A Systematic Literature Review’. Recent reviews conclude that the benefits of attending Specialist Palliative Day Care are likely to be in the social, psychological and spiritual domains. However these areas are not easily …
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Clinical review and experimental evaluation of tumour M2-pyruvate kinase in pancreatic cancer
The treatment of pancreatic cancer is challenging. Patients are often beyond curative surgical therapy and palliative treatment with chemotherapy provides limited benefit. New markers of cancer activity and therapeutic targets are required. This thesis has firstly reviewed the available literature …
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Repair and restitution in the gastrointestinal tract after exposure to a cancer chemotherapy drug.
… and to evaluate the efficacy of a possible palliative, a lectin. Rats were given 5-nuorouracil. This caused loss of rapidly dividing cells from the intestinal crypts and collapse of crypt / villus structure. By 2 days, few progenitor cells were evident. Nonetheless, cell division re-started …
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The experiences of primary caregivers providing palliative care to women living with advanced breast cancer
… and challenges of primary caregivers providing palliative care to women with advanced breast cancer. This study was conducted within a qualitative research design framework underpinned by phenomenology. The significance of this study was to contribute to the knowledge that would help care …
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Changing the way that doctors learn to care for people who are dying
… of work represents an interest in education in palliative care over the last ten years. These papers are written either by myself or in collaboration with colleagues in Britain and New Zealand. During those years the way in which palliative care is taught and learned has changed and continues to …
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Nurses' Knowledge of Palliative Care in a Midwestern Federal Medical Center
… assess the current knowledge and perceptions of palliative care of nurses in a Midwestern Veterans Affairs Medical Center (VAMC). The specific research questions were:<br> 1. What is the current state of knowledge of palliative care, current perceptions about nurses' spiritual role and current …
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Αποφρακτικός ίκτερος από ρήξη πρωτοπαθών νεοπλασμάτων του ήπατος εντός των χοληφόρων οδών
… carcinomas don't seem to change survival and the palliative treatment drainage using the insertion of T-tube into the bile duct is the only choice available. In conclusion we can say that the main characteristics of this complication are: a) the rarity b) the highest frequency to men c) the …
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Experimental and Computational Investigation of Tacrine-Based Inhibitors of Acetylcholinesterase
… Inhibition of AChE has proven an effective treatment for the memory loss exhibited by early stage Alzheimer's disease (AD) patients; four AChE inhibitors (AChEI) have been approved by the FDA for this purpose. The first AChEI approved for the palliative treatment of AD-related memory loss …
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The nutrition and hydration of older adult cancer patients in hospice
… given tube feeding, and emphasis is placed on palliative treatment. The purpose of the first project was to describe the dietary intake of twelve older adult cancer patients in home hospice care. The mean daily intakes of energy for males ranged from 657 to 2142 kcal per day, or from 28 to 93% …
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New Synthetic Polyamines as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease and Cancer: Design, Synthesis and Biological Evaluation
… experience shows that AChE inhibition is a palliative treatment, and the simple modulation of a single target does not address AD aetiology. Research into newer and more potent anti-AD agents is thus focused on compounds whose properties go beyond AChE inhibition (such as inhibition of the …
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Music, death, and dying : a systematic review of hospice and palliative care literature
… AND DYING:A SYSTEMATIC REVIEW OF HOSPICE AND PALLIATIVE CARE LITERATUREByVirginia A. AndersonThe purpose of this research was to categorize, code and summarize articles and abstracts on music therapy and palliative care and hospice in order to highlight themes and trends, as well as provide …
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Developing and testing a pain management program for family caregivers of advanced cancer patients
Increasingly, advanced cancer patients are receiving care in the community supported by families and hospice home care services. However, little or no preparation is provided to family caregivers who assume this supportive role, often 24 hours per day. Pain management is consistently identified by …
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