Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"PagP"”.
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New Roles for PagP in the Bacterial Outer Membrane Stress Response
… replication within host tissues. The OM enzyme PagP catalyzes the transfer of palmitate from a glycerophospholipid to lipid A. Lipid A is the endotoxic portion of LPS responsible for transmembrane signalling to initiate the immune response. Palmitoylation of lipid A can either attenuate or …
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Construction and characterization of proteome-minimized OMVs from E. coli and their exploitation in infectious disease and cancer vaccines
… in the LPS biosynthetic pathway (msbB and pagP) were subsequently inactivated creating E. coli BL21(DE3)Δ60 which released OMVs with a substantially reduced reactogenicity. The exploitation of the two strains in vaccine applications was finally validated. We successfully engineered E. …