Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Pachytene"”.
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Cytology, Mode of Reproduction, and Forage Quality of Selected Species of Brachiaria Griseb. (Chromosome Numbers, Fiber Structure, Pachytene Analysis, Apomixis)
… were found. A study of chromosome morphology at pachytene in B. ruziziensis was also undertaken. All nine members of the complement were identified based on centromere position, arm ratio, and size distribution of chromomeres. An idiogram was prepared for this species for the first time. Five …
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Meiotic Dna Re-Replication And The Recombination Checkpoint
… Therefore, indicating that induction of the pachytene checkpoint by a gene deletion of <em>DMC1</em> was responsible for meiotic DNA re-replication. The downstream targets of the meiotic recombination checkpoint, Ndt80, Sum1, and Swe1, which function to maintain arrest in the pachytene stage …
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Chromosome studies in the genera Lycopersicon and Solanum
… Lycopersicon and Solanum. Part I was a study of pachytene in Lycopersicon and began as an attempt to assess the usefulness of this stage as a source of information to aid classification. The principal findings of this thesis were as follows: 1. Chromosomes at pachytene were examined by the …
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Insights into the piRNA pathway through 16 strains of mice
… Element (TE)-mapping piRNAs across fetal pre-pachytene piRNAs, postnatal pre-pachytene piRNAs and pachytene piRNAs. Overall, TE-mapping piRNAs predominantly overlap with LINE and LTR transposon elements. Using Trinity RNA transcript assemblies with piRNA mapping, I identify previously …
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Mouse hybrid sterility genes linked to chromosome X
… testes, no sperm in the epididymis, meiotic pachytene arrest, and high rates of asynapsed autosomes. The first hybrid sterility locus in vertebrates was mapped to chromosome 17 and named Hybrid sterility 1 (Hst1), which was later identified as Prdm9 gene. The Prdm9-interacting hybrid …
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C. Elegans OMA-1 and OMA-2 are Transcriptional and Translational Repressors of Germline Fate
… A zif-1 3'UTR reporter is repressed in the pachytene and proximal regions of the adult C. elegans germline, and expression of the reporter is activated in the 4-cell embryo only in anterior blastomeres, reciprocal to the PIE-1 expression pattern. I show that zif-1 3'UTR reporter is repressed …
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P450 aromatase expression in germ cells and sperm of the adult mouse and rat testis and epididymis
… in adult rat germ cells as early as the pachytene spermatocyte stage of development. These data clearly demonstrate that testicular germ cells of the adult mouse and rat are able to synthesize active P450arom, and that there is a decrease in P450arom expression in sperm as they undergo …
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Meiotic defects in infertile men
… quadrivalents were observed in 90% and 87% of pachytene nuclei from the first and second biopsies, respectively, and were frequently associated with the sex chromosomes. BRCA1 and γH2AX, two proteins implicated in meiotic sex chromosome inactivation, localized along asynapsed regions regardless …
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Ubiquitin Conjugase UBE2K Is Essential for Normal Rat Development and Spermatogenesis
… during meiosis-I that prevented the zygotene to pachytene spermatocyte transition. Based on known interactions of UBE2K, and the biochemical function of UBE2K as ubiquitin ligase, I hypothesized that UBE2K is a component of the PRC1 complex that ubiquitinates H2A to prevent transcription as a …
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Analysis of the role of the X/Y homologous gene family Xmr/Sly in murine spermiogenesis
… to the transcriptionally silent sex body in pachytene spermatocytes. However, evidence is provided that this meiotic protein is not XMR, with the antibody used in previous studies unable to recognise XMR. Instead, Xmr is predominantly transcribed in spermatids were it encodes a cytoplasmic …
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Reproductive and somatic functions of RAD51A and BRCA2 genes in maize
… was also investigated in male zygotene and pachytene meiocytes. ZYP1, a protein involved in pairing homologous chromosomes, was localized in these cells. As predicted, rad51a1/rad51a2 and brca2 mutants had impaired ZYP1 axis formation compared to wild type; ZYP1 co-localized with DNA but …
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Characterization of the Genes Essential for Mouse Spermatogenesis
… and <italic>Dicer</italic>-null pachytene spermatocytes or round spermatids. Although levels of sex-linked mRNAs were mildly elevated, meiotic sex chromosome inactivation appeared to have occurred normally in both <italic>Drosha</italic> and <italic>Dicer</italic> cKO cells. Our …
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Regulating transcript fate through RNA elements in the 3' untranslated region
… Postnatal day 17 corresponds to the emergence of pachytene spermatocytes; postnatal day 21 corresponds to the emergence of round spermatids; and adult testis tissue can be assumed to correspond with the emergence of elongating spermatids, since mature spermatozoa have stopped translation. Hecht's …
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Lamin C2
In der Kernlamina von Spermatozyten von Nagetieren sind die Lamin A-Genprodukte, Lamin A und C, durch eine meiosespezifische Splicingvariante ersetzt. Dieses Lamin C2 unterscheidet sich auffallend von den somatischen Varianten in Struktur, Menge und Verhalten. Durch eine ektopische Expression von …