Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"PUF Protein"”.
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Microscopic characterization of a putative ER-membrane targeted Puf RNA-binding protein in Arabidopsis thaliana
… RNAs (mRNAs) are associated with RNA-binding proteins (RBPs) that form ribonucleoprotein (RNP) complexes. These RNP complexes are the functional units that participate in post-transcriptional gene regulation activities. One group of RBPs that plays an important role in regulating cytoplasmic …
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The PUF proteins in Trypanosoma brucei
… regulated at the post-transcriptional level. Proteins with an RNA-binding "Puf" domain are important for post-transcriptional control by modulation of mRNA stability and regulation of translation in other species. This suggested that Puf domain proteins might also have a similar role in …
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Study and engineering of nucleic acid-binding repeat proteins
… biology are governed by interactions between proteins and nucleic acids. Some of the nucleic acid-binding proteins have evolved repetitive structures and a modular sequence recognition mode. In particular, DNA-binding transcription activator-like effectors (TALE) and RNA-binding Pumilio/fem-3 …
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Nucleic Acid Scaffold-dependent Proximity-mediated Enzyme Response (NASPER) - A Proof of Concept Study
… tumour mass. NASPER involves bringing two fusion proteins, each of which comprises a custom-designed PUF (Pumilio and FBF) RNA-binding protein and a protease, onto the hTERT RNA into close proximity to activate the protease which should lead to cell death. The proteases tested in this study are …