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Showing 1 to 18 of 18 for “"PTK"”.

  1. Einfluss des Tyrosinkinaseninhibitors PTK 787/ZK 222584 auf Vaskularisation und Wachstum intracerebraler Gliome der Ratte

    … des VEGFRezeptor-2 spezifischen RTK-Inhibitors PTK 787/ ZK 222584 auf Angiogenese und somit Wachstum maligner Gliome in einem Tiermodell. Verwendet wurden hierbei C6-Rattengliomzellen aus denen durch retrovirale Transfektion von VEGF cDNA in sense Richtung ein stark VEGF exprimierender Zellklon …

    wurz-thes Repository record for Einfluss des Tyrosinkinaseninhibitors PTK 787/ZK 222584 auf Vaskularisation und Wachstum intracerebraler Gliome der Ratte (opens in a new tab)

  2. Effect of Mitomycin C with different application method on rabbit corneal wound healing process after Excimer laser photortherapeutic keratectomy

    … laser phototherapeutic keratectomy in rabbit. PTK was performed in both eyes of 18 New Zealand white rabbits using Technolas 217™. After laser removal of the epithelium(40 um depth with the optical zone 6.0mm), stromal ablation of 100 um dept with the optical zone 6.0mm was performed. 12 eyes …

    ajou Repository record for Effect of Mitomycin C with different application method on rabbit corneal wound healing process after Excimer laser photortherapeutic keratectomy (opens in a new tab)

  3. Tyrphostin AG126 modulates Toll-like receptor (TLR) activation-induced functions in microglia by protein tyrosine kinase (PTK) -dependent and -independent mechanisms

    … Klasse synthetischer Protein-Tyrosin-Kinase (PTK)-Hemmer, die sich strukturell vom Tyrosin ableiten und dazu dienen, spezifisch Substratphosphorylierungen zu verhindern. Tyrphostin AG126 zeigte entzündungshemmende Eigenschaften in zahlreichen Tiermodellen von Erkrankungen. Dies schließt den …

    goettingen Repository record for Tyrphostin AG126 modulates Toll-like receptor (TLR) activation-induced functions in microglia by protein tyrosine kinase (PTK) -dependent and -independent mechanisms (opens in a new tab)

  4. Contrast preservation and constraints on individual phonetic variation

    … simultaneous lenition of Spanish intervocalic /ptk/ and /bdg/ in three dialects (Cuzco, Peru; Lima, Peru; and Valladolid, Spain) is examined. Cuzco is found to have the strongest productions for both /ptk/ and /bdg/, Lima the weakest for both, and Valladolid in between for both. That is, the …

    uiuc Repository record for Contrast preservation and constraints on individual phonetic variation (opens in a new tab)

  5. Asymmetrische Weitz-Scheffer-Epoxidierung mit optisch aktiven Hydroperoxiden oder Phasentransferkatalysatoren

    … optisch aktive Phasentransferkatalysatoren (PTK) IV zur asymmetrischen Epoxidierung von Enonen II mit racemischen Hydroperoxiden I genutzt, wobei vordergründig die kinetische Racematspaltung der verwendeten Hydroperoxide I untersucht werden sollte. Darauf aufbauend wurde eine höchst effektive …

    wurz-thes Repository record for Asymmetrische Weitz-Scheffer-Epoxidierung mit optisch aktiven Hydroperoxiden oder Phasentransferkatalysatoren (opens in a new tab)

  6. Szerződéskötés elektronikus környezetben – Az „internet-szerződések”

    … jól példázza az a tény is, hogy az hatályos Ptk. a szerződésekre vonatkozó általános szabályok között külön fejezetet biztosít az elektronikus úton történő szerződéskötés különös szabályainak. Ezzel az e-szerződéseknek a polgári jog rendszerében elfoglalt helye már a Ptk., mint anyajog …

    debrecen Repository record for Szerződéskötés elektronikus környezetben – Az „internet-szerződések” (opens in a new tab)

  7. Az üzletrész másokat megelőző megszerzésére irányuló jog és a vételi jog konkurenciája

    … kitérést arra a dogmatikai problémára is, hogy a Ptk. nem tekinti a dolog kategória alá tartozó fogalomnak az üzletrészt, adásvétel tárgya-ként viszont szigorúan kiköti, hogy az csak dolog lehet, annak az átruházásáról és birtokba adásáról lehet kizárólag szó. Az elővásárlási jog fejezet alatt …

    debrecen Repository record for Az üzletrész másokat megelőző megszerzésére irányuló jog és a vételi jog konkurenciája (opens in a new tab)

  8. The role of integrin mediated adhesion and signaling during Xenopus retinal development

    … the hypothesis that protein tyrosine kinase (PTK) activity is essential for Xenopus retinal development. Inhibition of tyrosine kinase activity blocked focal adhesion assembly in cultures of dissociated retinal neuroepithelial cells and XR1 glial cells. Application of PTK inhibitors to …

    iastate Repository record for The role of integrin mediated adhesion and signaling during Xenopus retinal development (opens in a new tab)

  9. Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Regulates Hematopoietic Stem Cell Self-Renewal

    … by signaling through protein tyrosine kinases (PTK) such as c-kit, Flt-3 and Tie2. PTKs work in concert with receptor protein tyrosine phosphatases (PTPs) to maintain cellular equilibrium. The functions of PTPs in counterbalancing PTK signaling in HSCs however remain incompletely understood. Our …

    duke Repository record for Protein Tyrosine Phosphatase Receptor Type S (PTPRS) Regulates Hematopoietic Stem Cell Self-Renewal (opens in a new tab)

  10. Untersuchungen zur physiologischen Rolle der Proteintyrosinkinase Syk in humanen Brustepithelzellen

    Die Proteintyrosinkinase (PTK) Syk wird ubiquitär in hämatopoetischen Zellen exprimiert und ist für die Weiterleitung von Signalen aktivierter Immunrezeptoren unerlässlich. Eine biologische Funktion von Syk wurde auch außerhalb hämatopoetischer Zellen postuliert. In Anbetracht dessen sollten in der …

    lmu-germany Repository record for Untersuchungen zur physiologischen Rolle der Proteintyrosinkinase Syk in humanen Brustepithelzellen (opens in a new tab)

  11. Biochemical and genetic analysis of the adaptor protein SH3P7 : insights from a newly generated knockout mouse

    … as a substrate for protein tyrosine kinase (PTK) after BCR activation. In addition to two protein-binding modules specific for filamentous actin, SH3P7 also contains an SH3 domain. The biochemical studies presented here, show that SH3P7 interacts via this domain with key components of …

    freiburg-diss Repository record for Biochemical and genetic analysis of the adaptor protein SH3P7 : insights from a newly generated knockout mouse (opens in a new tab)

  12. Specificity of SH2 domains and protein tyrosine phosphatases

    … that are themselves protein tyrosine kinases (PTKs) or have an associated PTK activity. SH2 domains and protein tyrosine phosphatases (PTPs) play essential roles in transmitting these signals. SH2 domains are small domains of V100 amino acids that bind to phospho-tyrosine (pY) in the context of …

    concordia Repository record for Specificity of SH2 domains and protein tyrosine phosphatases (opens in a new tab)

  13. Autocrine mechanisms of action of insulin-like growth factor-I (IGF-I) and hormonal regulation of expression of IGF-finding proteins in mammary epithelial cells

    … and herpes simplex thymidine kinase (pTK-IGF-I) promoters. Stably transfected clones were generated by cotransfection of clonal MAC-T cells with the IGF-I expression vectors and a plasmid conferring resistance to hygromycin-B (HYG-B), using a calcium phosphate precipitation procedure. …

    vt Repository record for Autocrine mechanisms of action of insulin-like growth factor-I (IGF-I) and hormonal regulation of expression of IGF-finding proteins in mammary epithelial cells (opens in a new tab)

  14. Multi-Sincronização em menssage sequence charts

    … ainda, o uso da ferramenta Power Tool Kit(PTK) para geração de casos de teste a partir de diagramas MSC

    brazil-ufpe Repository record for Multi-Sincronização em menssage sequence charts (opens in a new tab)

  15. Intracellular signalling by arachidonic acid metabolites

    … with a PPAR-response element reporter construct (pTK-PPREx3-luc). The PPAR-γ-specific ligand, rosiglitazone, induced PPRE mediated activity in a concentration-dependent manner, while the PPAR-γ-specific irreversible inhibitor, GW9662, fully inhibited this induction. However, GW9662 only partially …

    auckland-ms Repository record for Intracellular signalling by arachidonic acid metabolites (opens in a new tab)

  16. Integrin-vermittelte Invasion von Staphylococcus aureus in Säugerzellen

    … der Src Familie. Die Protein Tyrosin Kinase (PTK) FAK ist nach Integrinstimulierung eines der Schlüsselenzyme in FK. Dies war der Anlass nach der Bedeutung von FAK für die Integrin-vermittelte Internalisierung von S. aureus zu fragen. Ebenfalls ein wichtiger Hinweis waren die starken …

    wurz-thes Repository record for Integrin-vermittelte Invasion von Staphylococcus aureus in Säugerzellen (opens in a new tab)

  17. CD40 stimulation activates ‘post-activated’ B Cells which are hyporesponsive to B Cell receptor and toll-like receptor 9 stimulation in autoimmunity

    … phosphorylation of the protein tyrosine kinase (PTK) spleen tyrosine kinase (Syk) and reduced intracellular Ca2+ release in SLE B cells [14]. Further studies reported reduced responsiveness of SLE B cells to TLR9 stimulation which recognizes nuclear antigens and is considered key in …

    tu-berlin Repository record for CD40 stimulation activates ‘post-activated’ B Cells which are hyporesponsive to B Cell receptor and toll-like receptor 9 stimulation in autoimmunity (opens in a new tab)