Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"PTH1R"”.
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Expression and Function(s) of Parathyroid Hormone- Related Peptide in Intramembranous Bone Formation by Neonatal Rat Calvarial Cells In Vitro
… the expression of PTHrP and its receptor (PTH1R) by osteogenic cells involved in intramembranous ossification in vitro, and to determine the effect of exogenous PTHrP on this process. Cells isolated from calvariae of neonatal rats were treated continuously or intermittently with PTHrP …
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Computational and experimental investigation of G protein-coupled receptor signalling mechanisms
… signalling. The Parathyroid Hormone Receptor 1 (PTH1R) was mechanistically modelled to investigate mutations in GNAS, the gene encoding the Gαs protein. These mutations are linked to the rare iiimetabolic disease pseudohypoparathyroidism (PHP) type 1c (PHP1c). The modelling involved abstraction …
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Activation mechanisms of non-class A G protein-coupled receptors
… (GLP1R), Parathyroid Hormone 1 receptor (PTH1R), Secretin Receptor (SCTR) and Pituitary Adenylate Cyclase 1 receptor (PAC1R), and fungal Class D receptor STE2, using large-scale all atom unbiased molecular dynamics simulations. To overcome the limitations associated with traditional MD …