Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 76 for “"PTH"”.
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PTH RESISTANCE SYNDROMES: AGE-DEPENDENT CLINICAL PICTURE AND EMERGING UNCOMMON FEATURES
BACKGROUND: The term “PTH resistance syndromes” refers to a group of diseases so far named pseudohypoparathyroidism (PHP). The improvement of knowledge on pathophysiology and genetic background led to the proposal of a new classification that encompasses all the diseases caused by mutations within …
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Osteoporosis in elderly women; Bone traits, fracture and the PTH gene complex
… for approximately 70-80%. Parathyroid hormone (PTH) is the key regulator of calcium homeostasis in the human organism and in addition a powerful skeletal anabolic agent when administered as a drug. Dual energy X-ray absorptiometry (DXA) is the standard method for assessing bone mineral density …
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Evaluación final del Proyecto capacitación popular sobre el manejo del agroecosistema del trópico húmedo (PTH), Pancasan-Matagalpa, 1993-1996
… con la incidencia del Proyecto Trópico Húmedo (PTH) con relación a los ingresos de los productores no participantes del Proyecto o Población No Meta (PNM). Este comportamiento refleja que los participantes del PTH han logrado mejorías sustanciales en la disponibilidad del recurso económico así …
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The role of boron alone or in combination with estrogen or PTH in the treatment of postmenopausal osteoporosis in ovariectomized rats
… with estrogen or parathyroid hormone (PTH) on bone quality and Ca, P, and Mg metabolism were investigated in 12- week-old rats. Treatment began on day 43 after ovariectomy and continued for 5 weeks. Treatments included 5 ppm (5 mg per kg diet) boron as boric acid, 17β estradiol (30 …
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The Impact of Depleting the Essential Bacterial Enzyme Peptidyl-tRNA Hydrolase on Translation
Peptidyl-tRNA hydrolase (Pth) is an essential bacterial enzyme that recycles peptidyl-tRNAs (pep-tRNAs) by hydrolyzing the ester bond between the tRNA and the peptide. The best-characterized function of Pth is salvaging free pep-tRNAs that dissociate from the ribosome during translation to prevent …
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Possible Effects of Voice Fundamental Frequency, Gender and Tongue Position on Phonation Threshold Pressure
Phonation threshold pressure (Pth) refers to the minimum lung pressure required to initiate phonation. Pth was studied as a function of voice fundamental frequency (f₀), gender, and tongue position. Ten adult native speakers of American English (five men and five women) with no known history of …
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The effect of continuous infusion of human parathyroid hormone on bone architecture in female mice
… continuous infusion of parathyroid hormone (PTH) in adult female mice, and to subsequently study the catabolic effects of PTH. Osmotic pumps were implanted subcutaneously and infused either vehicle, 40 pg/kg/day of PTH or 80 pg/kg/day of PTH for either 2 week or 4 week duration. Total body …
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Signalling to intracellular Ca2+ channels
… expressing type 1 parathyroid hormone receptors (PTH$_{1}$R), PTH(1-34) potentiated carbachol-evoked Ca$^{2+}$ release via a mechanism that required local delivery of cAMP to IP$_{3}$ receptors (IP$_{3}$R) within signalling junctions. My aim was to establish whether the interaction between …
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PARATHYROID HORMONE ACTIVITY AND RELATED CLINICOPATHOLOGICAL ALTERATIONS IN DOGS AFFECTED WITH CHRONIC KIDNEY DISEASE
… the determination of parathyroid hormone (PTH) concentration is not routinely due to limited available and validated method and need of radioimmunoassay. In CKD, data about the presence of RHPT in large populations of dogs and the thorough investigation of the association of PTH and other …
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Analysis of the Structure and Cell-Specific Transcription of the Bovine Parathyroid Hormone Gene (Micrococcal Nuclease)
Two EcoR I restriction fragments containing PTH gene sequences were isolated from a partial bovine library prepared using EcoR I cleaved high molecular weight bovine DNA and lambda phage charon 30 as a cloning vector. Restriction and sequence analyses of the two fragments indicate that they are …
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The Regulation of Glucose Metabolism during Osteoblast Differentiation
… to two different bone anabolic signals, WNT and PTH. I have further elucidated the mechanism underlying the metabolic changes, and have explored the functional importance of such changes for bone anabolism.</p> <p>Osteoblasts, the principal bone-forming cells, are differentiated from mesenchymal …
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Modulation Of Renin Secretion By Renal Cortical Interstitial Calcium
… cortical interstitium, and parathyroid hormone (PTH) positively regulates the concentration of calcium in the renal interstitium. Thus, we hypothesized that hypercalcemia inhibits PRA via PTH-mediated increases in renal cortical interstitial Ca that act on the CaSR triggering Ca-mediated …
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Characterizing the Development of Secondary Hyperparathyroidism and Vitamin D Resistance in Experimental Chronic Kidney Disease
… phosphate via secretion of parathyroid hormone (PTH) that acts on kidneys and bone to regulate mineral homeostasis. Hallmarks of chronic kidney disease (CKD) include increased retention of phosphate (PO4) and decreased renal production of 1,25-dihydroxyvitaminD3 (calcitriol) from its precursor, …
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Parathyroid hormone and calcium interactions in the periparturient mare
… concentrations of Ca and parathyroid hormone (PTH) that may be influenced by dietary Ca. Eight light mares from Farm A and eight Thoroughbred mares from Farm B were bled and milked 10 d pre-foaling, and eight mares (four from each farm) were bled and milked 5 d post-foaling. Milk Ca was …
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Changes of parathyroid hormone and vitamin D metabolites according to glomerular filtration rate in chronic kidney disease patients
… for elevations in serum parathyroid hormone (PTH) before they become frankly hypocalcemic. Quantification of the prevalence of these abnormalities has not been described using current assays in patients with non-dialysed chronic kidney disease in Korea. MATERIALS AND METHODS: Patients who had …
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An exploration of the calcium metabolic system in pregnancy and public health programmes to improve early nutrition in maternal-infant cohorts
… D [25(OH)D] and parathyroid hormone [PTH] were analysed in 1754 women in the SCOPE pregnancy cohort. While 25% of participants had a 25(OH)D concentration > 75 nmol/L, 17% were < 30 nmol/L. Functional vitamin D deficiency, defined as 25(OH)D < 30 nmol/L plus elevated PTH (> 80th …
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G-Protein gekoppelte Rezeptoren für Parathormon : molekulare Determinanten der intrazellulären Signalwegankopplung
… strukturellen und molekularen Determinanten der PTH-Rezeptoren für die Ankopplung an intrazelluläre Signalwege näher zu charakterisieren. Die Regulation des Kalzium-, Phosphat- und Knochenstoffwechsels wird zum erheblichen Teil über den PTH1-Rezeptor (P1R) vermittelt. Parathormon (PTH) aktiviert …
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Parathyroid hormone, calcitonin, serum and milk minerals in the periparturient dairy cow
… 21 days postpartum for parathyroid hormone (PTH), calcitonin (CT), Ca, magnesium (Mg), and phosphorus (P) analysis. Heifers and cows receiving the high Ca ration prepartum tended to have higher prepartum serum Ca. Cows fed the high Ca ration prepartum (hi-Ca cows) exhibited severe …
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Approaches to Improve the Structure and Function of the Skeleton in Chronic Kidney Disease
… chronically high levels of parathyroid hormone (PTH), which alters the balance of bone remodeling in favor of rampant osteoclast activity and bone resorption. Restricting cortical bone deterioration and the development of cortical pores is likely essential to improve CKD patients’ bone health and …
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Calcium metabolism and breast cancer risk
… i.e. vitamin D and parathyroid hormone (PTH), affect breast cancer risk. The associations between serum calcium levels and breast cancer risk, between serum calcium levels and known risk factors of breast cancer, and between serum calcium levels and breast cancer aggressiveness were …
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